Overview
Eicosapentaenoic acid ( CAS 10417-94-4 ), commonly known as EPA or Timnodonic acid, is a long-chain omega-3 fatty acid sourced primarily from marine oils and microalgae. It functions as a bioactive nutritional ingredient and pharmaceutical active across finished dosage forms.
In pharmaceutical manufacturing, EPA is incorporated into prescription-grade omega-3 concentrates and softgel capsules targeting cardiovascular and metabolic indications. High-purity concentrated forms are required to meet clinical dosing standards.
Functional food and dietary supplement producers use EPA to fortify products such as infant formula, nutrition bars, and enriched dairy. These are typically in encapsulated or emulsified formats to protect oxidation-sensitive material through processing.
In cosmetic and personal care formulations, EPA-enriched oils are used in anti-aging serums and barrier-repair creams. The fatty acid supports skin lipid matrix compatibility and overall dermal health in specialty topical applications.
Aquaculture and animal nutrition manufacturers also source EPA-rich concentrates to optimize feed formulations for farmed fish and specialty livestock. This ensures the nutritional profile of the end products meets consumer expectations.
EPA is available as a free fatty acid, ethyl ester, or triglyceride concentrate in liquid form. Purity levels range from standard fish oil concentrates to highly refined grades exceeding 90% EPA content for specific uses.
Pharmaceutical-grade material is supplied to USP and EP specifications, while food-grade material conforms to FCC standards. Bulk supply is typically handled under nitrogen-blanketed, cold-chain conditions to preserve stability.
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Physical Properties
| Melting Point | −54-−53 °C(lit.) |
| Boiling Point | 439°C |
| Density | 0.943 g/mL at 25 °C(lit.) |
| Flash Point | 93 °C |
| Appearance | Colorless Oil |
| Color | Colorless to pale yellow |
| Form | liquid |
| Refractive Index | n 20/D 1.4977(lit.) |
| Log P | 6.232 (est) |
Safety & Handling
Danger GHS05 Hazard Statements H314 Causes severe skin burns and eye damage Precautionary Statements P260 Do not breathe dust/fume/gas/mist/vapours/spray. P264 Wash … thoroughly after handling. P280 Wear protective gloves/protective clothing/eye protection/face protection. P316 Get emergency medical help immediately. P321 Specific treatment (see … on this label). P363 Wash contaminated clothing before reuse. P405 Store locked up. P501 Dispose of contents/container in accordance with local regulations. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P301+P330+P331 Rinse mouth. Do NOT induce vomiting. P302+P361+P354 IF ON SKIN: Take off immediately all contaminated clothing. Rinse skin with water/shower. P305+P354+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Trade & Regulatory
| HS Code | 29161900 |
| UN Number | 3265 |
| ADR Class | 8 |
| Packing Group | III |
| Storage Class | 10 - Combustible liquids |
| WGK (Germany) | 3 |
Other Names
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Chemical Properties
- CAS Number
- 10417-94-4
- EC Number
- 233-891-7
- Mol. Weight
- 302.5
- HS Code
- 29161900
- Category
- Surfactants