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Pharmaceutical Intermediates

1-cyclohexylethanol

CAS: 1193-81-3

Overview

1-Cyclohexylethanol (CAS 1193-81-3 ), also known as cyclohexyl methyl carbinol, is a secondary aliphatic alcohol used as a solvent, carrier, and chemical intermediate across pharmaceutical and fragrance manufacturing.

Its FEMA 4794 designation supports its use in flavoring and fragrance applications where regulatory traceability is required. In pharmaceutical manufacturing, it functions as a synthetic intermediate.

It is used in the preparation of active ingredients and specialty compounds requiring a cyclohexyl-bearing alcohol backbone. Fragrance formulators incorporate it as a carrier and fixative component.

In fine fragrance and functional fragrance systems, its moderate volatility helps anchor scent profiles. Personal care manufacturers use it in formulations such as skin creams and hair products.

It is ideal where a solvent with low water miscibility is needed to stabilize oil-phase ingredients. It also serves as a building block in custom synthesis projects targeting chiral structures.

1-Cyclohexylethanol is supplied as a clear liquid in standard packaging suitable for laboratory, pilot, and commercial-scale procurement. Technical and high-purity grades are available for use.

Specifications are confirmed by GC purity analysis to ensure consistency. Sourcing is typically available in quantities ranging from kilogram samples through bulk drum orders for industrial needs.

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Physical Properties

Melting Point140 °C
Boiling Point189 °C
Density0.918 g/cm³ @ Temp: 20 °C
Flash Point163 °F
AppearanceColorless to light yellow Liquid
OdorClean, fresh aroma
Water Solubility5.163g/L at 24℃
Vapor Pressure36.8Pa at 24℃
Refractive Indexn 20/D 1.465(lit.)
Log P1.6 at 25℃

Safety & Handling

Warning GHS07 Hazard Statements H312 Harmful in contact with skin H315 Causes skin irritation H319 Causes serious eye irritation Precautionary Statements P264 Wash … thoroughly after handling. P280 Wear protective gloves/protective clothing/eye protection/face protection. P317 Get emergency medical help. P321 Specific treatment (see … on this label). P501 Dispose of contents/container in accordance with local regulations. P264+P265 Wash … thoroughly after handling. P302+P352 IF ON SKIN: Wash with plenty of water. P332+P317 Get emergency medical help. P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29061900
Storage Class10 - Combustible liquids
WGK (Germany)2

Other Names

cyclohexyl methyl carbinol | (1-hydroxyethyl)cyclohexane | Cyclohexanemethanolalpha-methyl- | alpha-Methylcyclohexanemethanol | 2-METHYLCYCLOHEXYLMETHANOL | Cyclohexanemethanolα-methyl- | α-Methylcyclohexanemethanol

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Chemical Properties

CAS Number
1193-81-3
EC Number
214-780-7
Mol. Weight
128.21
HS Code
29061900

Industries

Documentation