Overview
Penicillin V Potassium (CAS 132-98-9 ), also known as Penicillin VK and Phenoxymethylpenicillin Potassium, is the potassium salt form of the acid-stable oral penicillin antibiotic used as an active pharmaceutical ingredient.
Its water-soluble salt form makes it the preferred raw material for solid oral antibiotic formulations over the free acid. The primary application is in the manufacture of oral antibiotic tablets and capsules.
It serves as the API for treating bacterial infections in human medicine. In veterinary pharmaceutical production, it is incorporated into oral suspensions and bolus formulations targeting livestock and companion animals.
Pharmaceutical compounding operations source it for preparation of oral liquid suspensions, particularly pediatric formulations requiring precise dosing flexibility. This ensures accurate administration for sensitive patient groups.
In biotechnology and life sciences, it is used as a selective agent in cell culture media to control bacterial contamination during research workflows. This maintains the integrity of experimental results.
Penicillin V Potassium is supplied as a white crystalline powder in bulk quantities suited to pharmaceutical manufacturing scale. Standard grades include USP , BP , and Ph. Eur. for compliance.
The potency is typically expressed in International Units (IU) per milligram to ensure standardized efficacy. Packaging ranges from kilogram-scale laboratory quantities to multi-hundred kilogram drums.
These industrial API procurement options support both small-scale research and large-scale commercial production. The material meets rigorous global quality standards for pharmaceutical distribution.
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Physical Properties
| Melting Point | 120-128 °C (decomp) |
| Density | 1.40 |
| Color | Sol in water |
| Form | neat |
| Water Solubility | Soluble in water, dimethyl sulfoxide, and methanol. |
Safety & Handling
Danger GHS07 GHS08 Hazard Statements H302 H302 H317 H317 H334 H334 Precautionary Statements P233 P233 P260 P260 P261 P261 P264 P264 P270 P270 P271 P271 P272 P272 P280 P280 P284 P284 P321 P321 P330 P330 P403 P403 P501 P501 P301+P317 P301+P317 P302+P352 P302+P352 P304+P340 P304+P340 P333+P317 P333+P317 P342+P316 P342+P316 P362+P364 P362+P364
Trade & Regulatory
| HS Code | 29411099 |
| WGK (Germany) | 3 |
Other Names
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Chemical Properties
- CAS Number
- 132-98-9
- EC Number
- 205-086-5
- Mol. Weight
- 388.5
- HS Code
- 29411099
- Category
- Pharmaceutical Intermediates