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Salts & Minerals

Calcium gluconate

CAS: 299-28-5

Overview

Calcium gluconate (CAS 299-28-5 ), also known by its food additive designation E578 , is a calcium salt of gluconic acid used across food, pharmaceutical, and personal care manufacturing.

It functions as a mineral supplement, pH buffer, and chelating agent depending on the application context. In food and beverage production, it acts as a firming agent and acidity regulator.

This ingredient maintains texture in canned vegetables and processed dairy products. Pharmaceutical manufacturers use it as a direct calcium source in oral and injectable mineral supplement formulations.

In personal care, it buffers pH and chelates metal ions in skincare and haircare products. This improves formulation stability and extends shelf life for a wide variety of consumer goods.

Food-grade calcium gluconate also serves as a sequestrant in baking and dairy processing. Controlling free calcium ions in these environments directly affects the final texture and consistency.

The material is supplied as a white crystalline powder or granules. Standard grades include USP , BP , Ph. Eur. , and food-grade ( FCC ) to meet diverse industry requirements.

Pharmaceutical grades meet strict purity thresholds for injectable and oral dosage applications. Packaging typically ranges from 25 kg bags to bulk quantities depending on the intended grade.

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Physical Properties

Melting Point120 °C
Boiling Point400°C[at 101 325 Pa]
Density1.677[at 20℃]
Appearancewhite crystalline powder or granules
ColorWhite
Odorat 100.00?%. odorless
FormCrystals or Crystalline Powder
Water Solubility3.3 g/100mL
Vapor Pressure0.004Pa at 20℃
pHpH;6.0~8.0
Log P-5.31 at 20℃

Trade & Regulatory

HS Code38220090
WGK (Germany)1

Other Names

E578 | D-gluconic acidcalcium salt (2:1) | D-Gluconic acid calcium salt | Calcium gluconateanhydrous | Calcium di-gluconate | Calciofon | Calcii gluconas | Calcarea gluconica

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Chemical Properties

CAS Number
299-28-5
EC Number
206-075-8
Mol. Weight
430.37
HS Code
38220090

Industries

Documentation