Overview
Sulisobenzone (CAS 4065-45-6 ), also marketed as Benzophenone-4, is a water-soluble UV absorber that protects formulations and substrates from UV-induced degradation across a broad absorption range.
Its water solubility distinguishes it from most benzophenone-series UV filters, making it the preferred choice where oil-free or aqueous systems are required for specific industrial applications.
In personal care, it is incorporated into sunscreens, hair care products, and leave-on formulations to provide UV protection in water-based systems where oil-soluble filters are incompatible.
Coatings and ink manufacturers use it to prevent photodegradation of pigments and binders in aqueous coatings, paper coatings, and packaging inks, extending print and coating durability under light exposure.
Adhesive and sealant formulators add it to water-borne systems to stabilize polymer matrices against UV-driven yellowing and embrittlement during the lifecycle of the finished product.
It also functions as a UV stabilizer in textile treatment liquors, protecting dyed fabrics from light-induced color fading and maintaining the aesthetic integrity of the treated materials.
Sulisobenzone is supplied as a white to off-white crystalline powder. Cosmetic-grade material meeting USP and Ph.Eur. specifications is standard for personal care applications.
Technical-grade material is also available for industrial coatings and ink end uses, ensuring high performance and stability across various manufacturing and chemical processing sectors.
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Physical Properties
| Melting Point | 145 °C |
| Boiling Point | 491 °C |
| Density | 1.4574 (rough estimate) |
| Flash Point | 0°C |
| Appearance | white to yellowish powder |
| Color | White to Off-White |
| Form | neat |
| Water Solubility | 300.92g/L at 25℃ |
| Vapor Pressure | 0Pa at 25℃ |
| Refractive Index | 1.5300 (estimate) |
| Log P | 0.515 at 25℃ |
Safety & Handling
Danger GHS05 GHS07 Hazard Statements H315 Causes skin irritation H317 May cause an allergic skin reaction H318 Causes serious eye damage H319 Causes serious eye irritation H335 May cause respiratory irritation Precautionary Statements P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P264 Wash … thoroughly after handling. P271 Use only outdoors or in a well-ventilated area. P272 Contaminated work clothing should not be allowed out of the workplace. P280 Wear protective gloves/protective clothing/eye protection/face protection. P317 Get emergency medical help. P319 Get medical advice/attention if you feel unwell. P321 Specific treatment (see … on this label). P405 Store locked up. P501 Dispose of contents/container in accordance with local regulations. P264+P265 Wash … thoroughly after handling. P302+P352 IF ON SKIN: Wash with plenty of water. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P332+P317 Get emergency medical help. P333+P317 Get emergency medical help. P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P403+P233 Store in a well-ventilated place. Keep container tightly closed. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P305+P354+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Trade & Regulatory
| HS Code | 29144000 |
| WGK (Germany) | 1 |
Other Names
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Chemical Properties
- CAS Number
- 4065-45-6
- EC Number
- 223-772-2
- Mol. Weight
- 308.31
- HS Code
- 29144000
- Category
- Organic Acids