Overview
Glycyrrhetinic acid (CAS 471-53-4 ), also known as uralenic acid, is a pentacyclic triterpenoid derived from licorice root extract. In personal care and cosmetics, it functions as a skin-conditioning active.
In flavoring applications, it contributes to the characteristic licorice taste profile of finished products. In cosmetic formulations, it is used in anti-inflammatory creams, serums, and spot-treatment products.
Formulators incorporate it into whitening and brightening preparations where it acts as a tyrosinase modulator. This helps to reduce the appearance of hyperpigmentation and redness in various skin types.
In the flavor industry, it is used as a flavoring agent and acidulant in confectionery and oral care products. It is also utilized in tobacco flavoring systems where a licorice character is required.
It appears in topical pharmaceutical preparations as a functional active in formulations addressing minor skin irritation. The material is supplied as a white to off-white crystalline powder for industrial use.
It is available in cosmetic-grade and pharmaceutical-grade specifications, with purity levels typically ranging from 95% to 98% by HPLC. These standards ensure high performance in sensitive applications.
Bulk quantities are offered in kilogram and multi-kilogram packaging to suit both development-scale and commercial production requirements. We ensure consistent quality for all global manufacturing needs.
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Physical Properties
| Melting Point | 296 °C |
| Boiling Point | 687.4 °C |
| Density | 0.9967 (rough estimate) |
| Appearance | white or greyish-white crystalline powder |
| Color | White to off-white |
| Form | Crystalline Powder |
| Water Solubility | SOLUBLE IN ACETIC ACID |
| Vapor Pressure | 10-220Pa at 20-50℃ |
| Refractive Index | 162 ° (C=1, MeOH) |
| Log P | 4.5 at 20℃ |
Safety & Handling
Warning GHS07 Hazard Statements H302 Harmful if swallowed H319 Causes serious eye irritation Precautionary Statements P264 Wash … thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P280 Wear protective gloves/protective clothing/eye protection/face protection. P330 Rinse mouth. P501 Dispose of contents/container in accordance with local regulations. P264+P265 Wash … thoroughly after handling. P301+P317 Get emergency medical help. P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Trade & Regulatory
| HS Code | 29189900 |
| Storage Class | 11 - Combustible Solids |
| WGK (Germany) | 3 |
Other Names
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Chemical Properties
- CAS Number
- 471-53-4
- EC Number
- 207-444-6
- Mol. Weight
- 470.7
- HS Code
- 29189900
- Category
- Flavors & Fragrances