Overview
Tetraethylene glycol monododecyl ether (CAS 5274-68-0 ), also known as tetraethylene glycol monolauryl ether, is a nonionic surfactant combining a C12 alkyl chain with a four-unit ethylene oxide head group.
It functions as an emulsifier, dispersant, and solvent carrier across industrial and personal care manufacturing. In personal care formulations, it emulsifies oil-in-water systems and solubilizes active ingredients.
This material is commonly found in cleansers, conditioners, and skin-care products. Textile and leather processing operations use it as a wetting and scouring agent to improve dye penetration and substrate uniformity.
Pharmaceutical manufacturers incorporate it as a solubilizing carrier for poorly water-soluble actives in topical and liquid formulations. It ensures stability and consistency in complex chemical mixtures.
In industrial cleaning compounds, its combined degreasing and dispersing action makes it effective in hard-surface and equipment cleaning concentrates. It remains stable across various pH levels and temperatures.
Tetraethylene glycol monododecyl ether is supplied as a clear to slightly hazy liquid at ambient temperature. Technical grade is the standard commercial offering for most industrial applications.
Higher-purity grades are available to meet pharmaceutical and personal care quality requirements. Packaging typically ranges from drums to intermediate bulk containers, depending on specific volume requirements.
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Physical Properties
| Melting Point | 18.6-19.0 °C |
| Boiling Point | 180-185 °C @ Press: 1 Torr |
| Density | 0.952 g/cm³ @ Temp: 20 °C |
| Flash Point | >230 °F |
| Appearance | white solid or colourless liquid |
| Color | Colorless to light yellow |
| Odor | at 100.00?%. mild alcoholic |
| Form | Liquid |
| Refractive Index | n 20/D 1.453 |
| Log P | 4.204 (est) |
Safety & Handling
Warning GHS07 GHS09 GHS05 Hazard Statements H302 Harmful if swallowed H315 Causes skin irritation H318 Causes serious eye damage H319 Causes serious eye irritation H335 May cause respiratory irritation H400 Very toxic to aquatic life H410 Very toxic to aquatic life with long lasting effects Precautionary Statements P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P264 Wash … thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P271 Use only outdoors or in a well-ventilated area. P273 Avoid release to the environment. P280 Wear protective gloves/protective clothing/eye protection/face protection. P317 Get emergency medical help. P319 Get medical advice/attention if you feel unwell. P321 Specific treatment (see … on this label). P330 Rinse mouth. P391 Collect spillage. P405 Store locked up. P501 Dispose of contents/container in accordance with local regulations. P264+P265 Wash … thoroughly after handling. P301+P317 Get emergency medical help. P302+P352 IF ON SKIN: Wash with plenty of water. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P332+P317 Get emergency medical help. P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P403+P233 Store in a well-ventilated place. Keep container tightly closed. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P305+P354+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Trade & Regulatory
| HS Code | 34029000 |
| UN Number | 3082 |
| ADR Class | 9 |
| Packing Group | III |
| Storage Class | 10 - Combustible liquids |
| WGK (Germany) | 2 |
Other Names
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Chemical Properties
- CAS Number
- 5274-68-0
- EC Number
- 226-097-1
- Mol. Weight
- 362.5
- HS Code
- 34029000
- Category
- Alcohols & Glycols