Isophorone

CAS: 78-59-1

Overview

Isophorone (CAS 78-59-1 ) is a cyclic ketone solvent used across industrial coatings, specialty chemical synthesis, and flavoring applications. With FEMA 3553 designation, it is also recognized in flavor formulation under the alternate commercial name Isoforone.

Its slow evaporation rate and strong solvency make it a preferred carrier in high-solids systems where controlled drying is critical. In coatings and lacquers, it dissolves nitrocellulose, epoxy, and polyurethane resins effectively.

This solvent supports high-build formulations where solvent balance directly affects film quality. It functions as a reaction medium and intermediate in the synthesis of isophorone diamine and isophorone diisocyanate.

These are key building blocks for polyurethane systems. In personal care manufacturing, it serves as a carrier solvent in nail lacquers and specialty cosmetic formulations requiring controlled evaporation rates for optimal application.

At permitted use levels, it contributes a fruity, herbal note to flavor compositions targeting baked goods and beverages. Isophorone is supplied as a clear liquid in drum and IBC quantities for various industrial needs.

Bulk tanker options are available for larger industrial volumes. Technical grade is the standard offering for coatings and synthesis applications. Food and flavor-compliant material is available to meet specific purity requirements.

This material is designed to meet the necessary standards for use in regulated flavor formulations. Our supply chain ensures consistent quality and availability for both industrial and food-grade applications globally.

Physical Properties

Melting Point	-8.1 °C
Boiling Point	215.32 °C
Density	0.9255 g/cm³ @ Temp: 20 °C
Flash Point	184 °F
Appearance	light yellow liquid
Color	Clear colorless to yellow
Odor	Like camphor.
Form	Liquid
Water Solubility	Soluble in water (12g/L).
Vapor Pressure	0.2 mm Hg ( 20 °C)
Refractive Index	n 20/D 1.476(lit.)
Log P	1.67-1.7 at 20℃

Safety & Handling

Warning GHS07 GHS08 Hazard Statements H227 Combustible liquid H302 Harmful if swallowed H312 Harmful in contact with skin H316 Causes mild skin irritation H319 Causes serious eye irritation H320 Causes eye irritation H333 May be harmful if inhaled H335 May cause respiratory irritation H336 May cause drowsiness or dizziness H351 Suspected of causing cancer Precautionary Statements P203 Obtain, consult and follow expert instructions for use. P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking. P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P264 Wash … thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P271 Use only outdoors or in a well-ventilated area. P280 Wear protective gloves/protective clothing/eye protection/face protection. P317 Get emergency medical help. P318 IF exposed or concerned, get medical advice. P319 Get medical advice/attention if you feel unwell. P321 Specific treatment (see … on this label). P330 Rinse mouth. P403 Store in a well-ventilated place. P405 Store locked up. P501 Dispose of contents/container in accordance with local regulations. P264+P265 Wash … thoroughly after handling. P301+P317 Get emergency medical help. P302+P352 IF ON SKIN: Wash with plenty of water. P304+P317 Get emergency medical help. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P332+P317 Get emergency medical help. P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P370+P378 Use … for extinction. P403+P233 Store in a well-ventilated place. Keep container tightly closed. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code	29142990
UN Number	3082
ADR Class	9
Packing Group	III
Storage Class	10 - Combustible liquids
WGK (Germany)	1

Other Names

Industries

Personal Care & Cosmetics Food & Nutrition