Thioglycerol

CAS: 96-27-5

Overview

Thioglycerol (CAS 96-27-5 ), also known as MTG, is a sulfur-containing diol used across pharmaceutical, cosmetic, and specialty chemical manufacturing. It functions primarily as a reducing agent and stabilizer.

This chemical protects sensitive compounds from oxidative degradation during formulation and processing. In pharmaceutical manufacturing, it stabilizes active ingredients prone to oxidation, extending shelf life in injectable and topical formulations.

Personal care formulators incorporate it into hair treatment products, where its thiol group participates in breaking and reforming disulfide bonds to reshape hair structure. It also acts as a humectant in cosmetic preparations.

This helps finished products retain moisture and maintain texture over time. In specialty chemical synthesis, MTG serves as a cross-linking agent and intermediate for producing thioether compounds used in polymer and resin systems.

Thioglycerol is supplied as a clear to pale yellow viscous liquid. Pharmaceutical-grade material is available to meet USP and BP specifications, while technical-grade material serves industrial synthesis applications.

Packaging typically ranges from small laboratory quantities up to bulk drum supply for commercial-scale production. This ensures that manufacturers can source the exact volume required for their specific industrial or laboratory needs.

Physical Properties

Melting Point	<25 °C
Boiling Point	118 °C @ Press: 5 Torr
Density	1.295 g/cm³
Flash Point	>230 °F
Appearance	clear colorless to yellowish viscous solution
Color	Clear colorless to yellow
Odor	Stench odour
Form	liquid
Water Solubility	slightly soluble
Vapor Pressure	<1 hPa (20 °C)
Refractive Index	n 20/D 1.527(lit.)
pH	3.5-7.0
Log P	-0.84 at 20℃

Safety & Handling

Danger GHS06 GHS07 Hazard Statements H302 Harmful if swallowed H311 Toxic in contact with skin H315 Causes skin irritation H317 May cause an allergic skin reaction H319 Causes serious eye irritation H331 Toxic if inhaled H335 May cause respiratory irritation Precautionary Statements P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P262 Do not get in eyes, on skin, or on clothing. P264 Wash … thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P271 Use only outdoors or in a well-ventilated area. P272 Contaminated work clothing should not be allowed out of the workplace. P280 Wear protective gloves/protective clothing/eye protection/face protection. P316 Get emergency medical help immediately. P319 Get medical advice/attention if you feel unwell. P321 Specific treatment (see … on this label). P330 Rinse mouth. P405 Store locked up. P501 Dispose of contents/container in accordance with local regulations. P264+P265 Wash … thoroughly after handling. P301+P317 Get emergency medical help. P302+P352 IF ON SKIN: Wash with plenty of water. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P332+P317 Get emergency medical help. P333+P317 Get emergency medical help. P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help. P361+P364 Take off immediately all contaminated clothing and wash it before reuse. P362+P364 Take off contaminated clothing and wash it before reuse. P403+P233 Store in a well-ventilated place. Keep container tightly closed. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code	29309070
UN Number	2810
ADR Class	6.1
Packing Group	III
Storage Class	6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects
WGK (Germany)	3

Other Names

Industries

Food & Nutrition Pharmaceuticals & Healthcare Personal Care & Cosmetics