Tripropylamine

CAS: 102-69-2

Overview

Tripropylamine (CAS 102-69-2 ), also abbreviated as TPA, is a tertiary aliphatic amine used across pharmaceutical synthesis, agrochemical manufacturing, and polymer chemistry. It functions primarily as a catalyst and pH buffer.

This chemical serves as a solvent in reactions requiring a non-nucleophilic base with moderate volatility. In pharmaceutical and fine chemical synthesis, it acts as a base catalyst or acid scavenger in condensation reactions.

Controlled basicity is critical to yield and purity during acylation processes. Agrochemical formulators use it to neutralize acidic herbicide and pesticide concentrates, improving stability and handling characteristics of the final formulation.

In polymer and resin production, it serves as a curing catalyst and process aid. This is particularly useful in systems where a slower-acting tertiary amine is preferred over more reactive alternatives in the manufacturing cycle.

Lubricant and metalworking fluid manufacturers incorporate it as a pH stabilizer to extend fluid service life. This application helps reduce corrosion in metal-cutting applications and maintains the integrity of industrial fluids.

The product is supplied as a clear liquid in standard drum and IBC quantities, with bulk tanker options available for high-volume industrial buyers. Technical grade is the most common commercial specification for this amine.

Purity is typically maintained at 99% or above to meet industrial requirements. It is also listed under FEMA 4247 , which is relevant for flavor and fragrance procurement channels requiring documented ingredient status.

Physical Properties

Melting Point	-93.5 °C
Boiling Point	156 °C
Density	0.7558 g/cm³ @ Temp: 20 °C
Flash Point	98 °F
Appearance	colourless liquid
Color	Clear colorless
Odor	at 0.10 % in propylene glycol. fishy ammoniacal
Form	Liquid
Water Solubility	2.6 g/L (20 ºC)
Vapor Pressure	2.9 mm Hg ( 20 °C)
Refractive Index	n 20/D 1.416(lit.)
pH	11.4 (2.6g/l, H2O, 20℃)
Log P	0.9 at 25℃

Safety & Handling

Danger GHS02 GHS05 GHS06 GHS07 Hazard Statements H226 Flammable liquid and vapor H301 Toxic if swallowed H311 Toxic in contact with skin H314 Causes severe skin burns and eye damage H315 Causes skin irritation H318 Causes serious eye damage H330 Fatal if inhaled H332 Harmful if inhaled H335 May cause respiratory irritation H402 Harmful to aquatic life H412 Harmful to aquatic life with long lasting effects Precautionary Statements P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking. P233 Keep container tightly closed. P240 Ground and bond container and receiving equipment. P241 Use explosion-proof [electrical/ventilating/lighting/…] equipment. P242 Use non-sparking tools. P243 Take action to prevent static discharges. P260 Do not breathe dust/fume/gas/mist/vapours/spray. P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P262 Do not get in eyes, on skin, or on clothing. P264 Wash … thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P271 Use only outdoors or in a well-ventilated area. P273 Avoid release to the environment. P280 Wear protective gloves/protective clothing/eye protection/face protection. P284 In case of inadequate ventilation wear respiratory protection. P316 Get emergency medical help immediately. P317 Get emergency medical help. P319 Get medical advice/attention if you feel unwell. P320 Specific treatment is urgent (see … on this label). P321 Specific treatment (see … on this label). P330 Rinse mouth. P363 Wash contaminated clothing before reuse. P405 Store locked up. P501 Dispose of contents/container in accordance with local regulations. P264+P265 Wash … thoroughly after handling. P301+P316 Get emergency medical help immediately. P302+P352 IF ON SKIN: Wash with plenty of water. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P332+P317 Get emergency medical help. P361+P364 Take off immediately all contaminated clothing and wash it before reuse. P362+P364 Take off contaminated clothing and wash it before reuse. P370+P378 Use … for extinction. P403+P233 Store in a well-ventilated place. Keep container tightly closed. P403+P235 Store in a well-ventilated place. Keep cool. P301+P330+P331 Rinse mouth. Do NOT induce vomiting. P302+P361+P354 IF ON SKIN: Take off immediately all contaminated clothing. Rinse skin with water/shower. P303+P361+P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/shower. P305+P354+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code	29211980
UN Number	2260
ADR Class	3
Packing Group	III
Storage Class	3 - Flammable liquids
WGK (Germany)	2

Other Names

Industries

Pharmaceuticals & Healthcare Agriculture & Feed Plastics & Polymers Lubricants & Metalworking