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Thiodipropionic acid

CAS: 111-17-1

Overview

Thiodipropionic acid (CAS 111-17-1 ), also known by the trade name Tyox A and abbreviated as TDPA, is a sulfur-containing dicarboxylic acid used industrially as an antioxidant and stabilizer.

Approved as E388 in food applications, it protects fats, oils, and polymers from oxidative degradation during processing and storage. It is a critical component for maintaining material integrity.

In plastics and polymer manufacturing, TDPA functions as a secondary antioxidant synergist, extending the service life of polyolefins and other thermoplastics when combined with hindered phenol primary antioxidants.

Food-grade applications include use as an antioxidant in edible fats and oils, where it inhibits rancidity and maintains product quality through extended shelf life. This ensures long-term stability for consumers.

In personal care formulations, it stabilizes lipid-rich creams and ointments against oxidative breakdown. Pharmaceutical manufacturers also employ TDPA as a stabilizer in formulations and as a precursor in synthesis.

The material is utilized in processes where controlled reactivity of the thioether group is required. Thiodipropionic acid is supplied as a white crystalline powder for easy handling and precise dosing.

Standard commercial grades include food-grade material meeting E388 specifications and technical-grade product for polymer and industrial applications. These meet rigorous global safety and performance requirements.

Packaging typically ranges from small quantities for specialty formulation work up to bulk quantities for industrial polymer producers. We ensure high quality standards for all industrial and food-grade shipments.

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Physical Properties

Melting Point134 °C
Boiling Point280.43°C (rough estimate)
Density1.238 (estimate)
Flash Point128 °C
AppearanceWHITE FINE CRYSTALLINE POWDER
ColorWhite
FormFine Crystalline Powder
Water Solubility40 g/L (25 ºC)
Vapor Pressure0.004Pa at 25℃
Refractive Index1.5500 (estimate)
Log P0.19 at 25.1℃

Safety & Handling

Danger GHS05 GHS07 Hazard Statements H314 Causes severe skin burns and eye damage H318 Causes serious eye damage H319 Causes serious eye irritation Precautionary Statements P260 Do not breathe dust/fume/gas/mist/vapours/spray. P264 Wash … thoroughly after handling. P280 Wear protective gloves/protective clothing/eye protection/face protection. P316 Get emergency medical help immediately. P317 Get emergency medical help. P321 Specific treatment (see … on this label). P363 Wash contaminated clothing before reuse. P405 Store locked up. P501 Dispose of contents/container in accordance with local regulations. P264+P265 Wash … thoroughly after handling. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help. P301+P330+P331 Rinse mouth. Do NOT induce vomiting. P302+P361+P354 IF ON SKIN: Take off immediately all contaminated clothing. Rinse skin with water/shower. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P305+P354+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29309070
Storage Class11 - Combustible Solids
WGK (Germany)2

Other Names

33'-Thiodipropionic acid | Tyox A | TDPA | Propanoic acid33'-thiobis- | Bis(2-carboxyethyl) sulfide | Thiodihydracrylic acid | 4-Thiaheptanedioic acid | Sulfidebis(2-carboxyethyl) | E388

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Chemical Properties

CAS Number
111-17-1
EC Number
203-841-3
Mol. Weight
178.21
HS Code
29309070

Industries

Documentation