Overview
Guanosine (CAS 118-00-3 ), abbreviated Guo, is a purine nucleoside consisting of guanine linked to a ribose sugar, produced for use across pharmaceutical synthesis and biotechnology research.
It functions as a biochemical building block and bioactive ingredient, supplying the guanosine unit required in nucleotide synthesis pathways and specialty cosmetic formulations for active ingredient development.
In pharmaceutical manufacturing, it serves as a key intermediate in the synthesis of antiviral and immunomodulatory compounds, where structural integrity and purity directly affect downstream API quality.
Biotechnology and life sciences applications include use in cell culture media, enzyme substrate studies, and nucleic acid research, where consistent lot-to-lot quality is critical for reproducible results.
In personal care formulations, it is incorporated into skin conditioning and moisturizing products, where its hygroscopic behavior supports water retention at the skin surface for premium skincare lines.
Contract formulators sourcing for cosmetic actives also evaluate it for surface-wetting and film-forming applications. The material is supplied as a white to off-white crystalline powder for industrial use.
It is available in pharmaceutical-grade specifications including USP and reagent-grade standards suited to research and API synthesis workflows across global manufacturing facilities.
Food-grade and cosmetic-grade variants are also offered depending on end-use compliance requirements, ensuring that the material meets the specific regulatory needs of the target market.
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Physical Properties
| Melting Point | 239 °C (decomp) |
| Boiling Point | 425.8°C (rough estimate) |
| Density | 1.3790 (rough estimate) |
| Appearance | Crystalline |
| Color | White to light yellow |
| Odor | Odorless |
| Form | Powder |
| Water Solubility | 0.75 g/L (25 ºC) |
| Refractive Index | -76 ° (C=1, 1mol/L NaOH) |
| pH | 2.14;9.03 |
| Log P | -2.331 (est) |
Safety & Handling
Danger GHS06 Hazard Statements H301 Toxic if swallowed Precautionary Statements P264 Wash … thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P321 Specific treatment (see … on this label). P330 Rinse mouth. P405 Store locked up. P501 Dispose of contents/container in accordance with local regulations. P301+P316 Get emergency medical help immediately.
Trade & Regulatory
| HS Code | 29349990 |
| UN Number | 2811 |
| ADR Class | 6.1 |
| Packing Group | III |
| Storage Class | 11 - Combustible Solids |
| WGK (Germany) | 3 |
Other Names
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Chemical Properties
- CAS Number
- 118-00-3
- EC Number
- 204-227-8
- Mol. Weight
- 283.24
- HS Code
- 29349990
- Category
- Amino Acids & Peptides