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Pharmaceutical Intermediates

Methyl salicylate

CAS: 119-36-8

Overview

Methyl salicylate (CAS 119-36-8 ), also sold as wintergreen oil, teaberry oil, and sweet birch oil, is a naturally occurring ester produced both by extraction and synthesis.

It functions as a flavoring agent, fragrance ingredient, UV absorber, and biocidal component across a broad range of industrial and consumer product formulations for various sectors.

In food and beverage manufacturing, it delivers the characteristic wintergreen flavor to confectionery, chewing gum, and oral care products under FEMA 2745 for global distribution.

Topical pharmaceutical and cosmetic formulators use it as a counterirritant active and fragrance fixative in muscle rubs, liniments, and analgesic creams for pain relief applications.

Coatings and ink manufacturers incorporate it as a UV stabilizer and solvent carrier, where its absorption profile helps protect substrates from photodegradation and environmental wear.

In adhesives and sealant systems, it also contributes antimicrobial preservation, extending shelf life in moisture-sensitive formulations and preventing degradation during long-term storage.

Methyl salicylate is supplied as a clear, mobile liquid in drum and IBC quantities. Food-grade material meeting FCC and FEMA specifications is standard for flavor and oral care applications.

Pharmaceutical-grade product conforming to USP and BP monographs is available for regulated topical formulations, ensuring compliance with strict international quality standards.

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Physical Properties

Melting Point-8.6 °C
Boiling Point220-224 °C
Density1.184 g/cm³ @ Temp: 25 °C
Flash Point226 °F
Appearancecolourless liquid with an odour of wintergreen
ColorClear colorless to pale yellow
Odorat 10.00 % in dipropylene glycol. wintergreen mint
FormLiquid
Water Solubility0.07 g/100 mL (20 ºC)
Vapor Pressure1 mm Hg ( 54 °C)
Refractive Indexn 20/D 1.536(lit.)
Log P2.55

Safety & Handling

Warning GHS07 GHS08 GHS05 Hazard Statements H302 Harmful if swallowed H314 Causes severe skin burns and eye damage H317 May cause an allergic skin reaction H318 Causes serious eye damage H319 Causes serious eye irritation H412 Harmful to aquatic life with long lasting effects Precautionary Statements P203 Obtain, consult and follow expert instructions for use. P260 Do not breathe dust/fume/gas/mist/vapours/spray. P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P264 Wash … thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P272 Contaminated work clothing should not be allowed out of the workplace. P273 Avoid release to the environment. P280 Wear protective gloves/protective clothing/eye protection/face protection. P316 Get emergency medical help immediately. P317 Get emergency medical help. P318 IF exposed or concerned, get medical advice. P321 Specific treatment (see … on this label). P330 Rinse mouth. P363 Wash contaminated clothing before reuse. P405 Store locked up. P501 Dispose of contents/container in accordance with local regulations. P264+P265 Wash … thoroughly after handling. P301+P317 Get emergency medical help. P302+P352 IF ON SKIN: Wash with plenty of water. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P333+P317 Get emergency medical help. P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P301+P330+P331 Rinse mouth. Do NOT induce vomiting. P302+P361+P354 IF ON SKIN: Take off immediately all contaminated clothing. Rinse skin with water/shower. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P305+P354+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29182300
Storage Class10 - Combustible liquids
WGK (Germany)1

Other Names

Teaberry oil | Sweet birch oil | Spicewood Oil | Oil of wintergreen | O-Hydroxybenzoic acidmethyl ester | Natural wintergreen oil | Methyl salicylate8CI | Methyl o-hydroxybenzoate

Related Products

Chemical Properties

CAS Number
119-36-8
EC Number
204-317-7
Mol. Weight
152.15
HS Code
29182300

Industries

Documentation