Overview
Methyl nicotinate (CAS 93-60-7 ), also known commercially as Heat Spray in topical applications, is the methyl ester of nicotinic acid used across pharmaceutical synthesis, flavor formulation, and cosmetic actives.
FEMA 3709 status confirms its recognized standing as a flavoring agent in food and beverage applications. In pharmaceutical manufacturing, it serves as a key intermediate in the synthesis of niacin derivatives.
It is utilized in active pharmaceutical ingredients targeting metabolic pathways. Food and beverage formulators use it as a flavoring agent, contributing roasted, meaty, or savory nuance to processed food products.
In personal care and cosmetic formulations, its vasodilatory effect on skin microcirculation makes it a functional active in warming creams, sports massage products, and topical heat-effect preparations.
Fragrance and flavor houses also source it as a building block for heterocyclic aroma compounds in tobacco and savory flavor profiles. Methyl nicotinate is supplied as a white to off-white crystalline solid.
Standard commercial grades include technical, food-grade, and pharmaceutical-grade material meeting USP or BP specifications. This ensures high purity for sensitive industrial and medical applications.
Packaging typically ranges from kilogram quantities up to bulk drum supply depending on grade and application requirements. We ensure consistent quality and supply chain reliability for all global shipments.
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Physical Properties
| Melting Point | 42.5 °C |
| Boiling Point | 102-104 °C @ Press: 15 Torr |
| Density | 1.2528 (rough estimate) |
| Flash Point | 204 °F |
| Appearance | white to brownish crystals or crystalline powder |
| Color | White to brownish |
| Odor | at 10.00 % in dipropylene glycol. warm herbal tobacco |
| Form | Crystals or Crystalline Powder |
| Water Solubility | NEGLIGIBLE |
| Vapor Pressure | 0.4 hPa (25 °C) |
| Refractive Index | 1.5323 (estimate) |
| Log P | 0.68 at 25℃ |
Safety & Handling
Warning GHS07 Hazard Statements H315 Causes skin irritation H319 Causes serious eye irritation Precautionary Statements P264 Wash … thoroughly after handling. P280 Wear protective gloves/protective clothing/eye protection/face protection. P321 Specific treatment (see … on this label). P264+P265 Wash … thoroughly after handling. P302+P352 IF ON SKIN: Wash with plenty of water. P332+P317 Get emergency medical help. P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Trade & Regulatory
| HS Code | 29333999 |
| WGK (Germany) | 3 |
Other Names
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Chemical Properties
- CAS Number
- 93-60-7
- EC Number
- 202-261-8
- Mol. Weight
- 137.14
- HS Code
- 29333999
- Category
- Heterocyclic Compounds