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Organic Acids

Trolamine salicylate

CAS: 2174-16-5

Overview

Trolamine salicylate (CAS 2174-16-5 ), also known as triethanolamine salicylate, TEA-Salicylate, and marketed under the trade name Neo Heliopan TS, is the salt formed between triethanolamine and salicylic acid.

It functions as both a UV-absorbing active and a topical analgesic agent across personal care and pharmaceutical applications. In sunscreen formulations, it absorbs UVB radiation in the 290–320 nm range.

This provides photoprotection in lotions, creams, and sprays without requiring insoluble mineral filters. Topical OTC analgesic products including muscle rubs, joint creams, and pain-relief gels rely on it as the active ingredient.

Its water solubility allows formulators to build clear, aqueous-phase sunscreen and cosmetic products where oil-soluble UV filters would compromise aesthetics. This makes it a versatile choice for localized pain management.

Pharmaceutical manufacturers also use it as an intermediate in developing salicylate-based dermatological preparations. It is supplied as a white to off-white crystalline powder or as an aqueous solution.

The material is available in cosmetic-grade and pharmaceutical-grade specifications, with the latter conforming to USP standards. This ensures high purity for sensitive medical and skincare applications.

Packaging typically ranges from kilogram quantities for formulators to bulk drum supply for industrial manufacturers. This flexibility supports both small-scale research and large-scale commercial production needs.

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Physical Properties

Density1.209 g/mL at 25 °C
Flash Point113 °C
Appearancepale yellow to amber crystalline solid
Odordull pleasent sweet
Formneat
Refractive Indexn20/D 1.509
Log P-1.108 (est)

Safety & Handling

Warning GHS07

Trade & Regulatory

HS Code29225000
WGK (Germany)3

Other Names

Triethanolamine salicylate | TEA-Salicylate | Neo heliopan ts | Neotan w | H8O4040BHD | Benzoic acid2-hydroxy-compd. with 22′2′′-nitrilotris[ethanol] (1:1) | Salicylic acidcompd. with 22′2′′-nitrilotriethanol (1:1) | Ethanol22′2′′-nitrilotris-2-hydroxybenzoate (salt)

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Chemical Properties

CAS Number
2174-16-5
EC Number
218-531-3
Mol. Weight
287.31
HS Code
29225000

Industries

Documentation