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Pharmaceutical Intermediates

S-adenosyl-L-methionine chloride

CAS: 24346-00-7

Overview

S-adenosyl-L-methionine chloride (CAS 24346-00-7 ), also known as SAM chloride, is a stabilized salt form of the endogenous methyl donor S-adenosylmethionine used across pharmaceutical, nutraceutical, and biotechnology applications.

It functions primarily as a methyl group donor in enzymatic synthesis and as an active ingredient in formulations targeting liver health and mood support categories. In pharmaceutical manufacturing, it serves as a key intermediate.

SAM chloride is used in finished dosage forms including tablets, enteric-coated formulations, and injectables. Nutraceutical and dietary supplement producers use it as the active ingredient in joint support and cognitive health products.

Stable salt forms are preferred over free-base material for processing in these industries. Biotechnology researchers rely on it as a cofactor and reagent in methyltransferase assays and epigenetic research workflows.

Food-grade applications include functional food fortification where methyl donor supplementation is a defined formulation objective. It is supplied as a crystalline powder, typically in stabilized salt form to maintain activity.

Material is available in pharmaceutical-grade specifications aligned with USP and BP monograph requirements, as well as research-grade lots for life sciences use. This ensures high purity for sensitive applications.

Bulk quantities are offered for industrial formulation, with smaller pack sizes available for laboratory and development-scale procurement. This flexibility supports both large-scale manufacturing and R&D projects.

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Physical Properties

ColorOff-White to Dark Yellow
FormSolid

Trade & Regulatory

WGK (Germany)1

Other Names

S-adenosylmethionine chloride | SAM chloride | B02SK72839 | ADEMETIONINE CHLORIDE | (3S)-5'-((3-Amino-3-carboxypropyl)methylsulphonio)-5'-deoxyadenosine chloride | Adenosine5′-[(3-amino-3-carboxypropyl)methylsulfonio]-5′-deoxy-chloride | MethionineS-(5-deoxyadenos-5-yl)-chlorideL- | Adenosine5′-[[(3S)-3-amino-3-carboxypropyl]methylsulfonio]-5′-deoxy-chloride

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Chemical Properties

CAS Number
24346-00-7
EC Number
246-184-8
Mol. Weight
434.9

Industries

Documentation