Overview
Dipalmitoyl hydroxyproline (CAS 41672-81-5 ), also known commercially as LIPACIDE DPHP, is a lipophilic derivative of hydroxyproline used in personal care formulations.
It combines a fatty acid component with an amino acid to deliver moisturizing and stabilizing activity within oil-based systems. Formulators source it primarily as a skin-conditioning active.
In facial and body care emulsions, it functions as a humectant that supports moisture retention within the lipid phase of the formulation. It is incorporated into anti-aging creams and serums.
Its antioxidant properties help protect formulation integrity and support skin barrier function. Hair care products such as conditioning treatments use it to deliver amino acid-derived benefits.
Its lipophilic character also suits it for anhydrous formats including balms, sticks, and oil serums where water-soluble actives cannot be used effectively in the manufacturing process.
Dipalmitoyl hydroxyproline is typically supplied as a waxy solid or powder suitable for incorporation into the oil phase of cosmetic formulations. It is available in cosmetic-grade specification.
This is the standard for personal care raw material procurement. Packaging is commonly offered in kilogram quantities for development-scale sourcing through to larger bulk formats for production.
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Physical Properties
| Boiling Point | 696.6±55.0 °C(Predicted) |
| Density | 0.98±0.1 g/cm3(Predicted) |
| Water Solubility | 1mg/L at 20℃ |
| Vapor Pressure | 0Pa at 25℃ |
| Log P | 7 |
Safety & Handling
Warning GHS07 Hazard Statements H319 Causes serious eye irritation H412 Harmful to aquatic life with long lasting effects Precautionary Statements P273 Avoid release to the environment. P280 Wear protective gloves/protective clothing/eye protection/face protection. P501 Dispose of contents/container in accordance with local regulations. P264+P265 Wash … thoroughly after handling. P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Other Names
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Chemical Properties
- CAS Number
- 41672-81-5
- EC Number
- 255-490-0
- Mol. Weight
- 607.9
- Category
- Oils, Fats & Waxes