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Pigments & Colorants

Genistein

CAS: 446-72-0

Overview

Genistein (CAS 446-72-0 ), also known as Prunetol and Genisteol, is a naturally occurring isoflavone extracted primarily from soy and other leguminous plants.

It functions as a phytoestrogen and antioxidant active across pharmaceutical, nutraceutical, and cosmetic applications. Buyers source it both as a purified reference-grade material and as a standardized botanical extract.

In nutraceutical and dietary supplement manufacturing, it is formulated into capsules, tablets, and functional foods targeting hormonal balance and bone health support for various consumer demographics.

Pharmaceutical developers use it as an intermediate in the synthesis of isoflavone-based compounds and as an active ingredient in investigational formulations requiring high purity and strict quality control.

Cosmetic formulators incorporate it into anti-aging creams and serums where its antioxidant activity supports skin surface stabilization and oxidative stress reduction for topical applications.

Food-grade applications include fortified beverages and soy-derived functional ingredients where standardized isoflavone content is a key quality parameter for manufacturers and industrial food processors.

The material is supplied as an off-white to pale yellow powder in technical and high-purity grades. Standardized extract forms, such as 85% HPLC, are commonly available for formulation work.

Reagent and reference-standard grades are also offered to support analytical and pharmaceutical development workflows, ensuring compliance with global chemical and nutritional safety regulations.

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Physical Properties

Melting Point301.5 °C (decomp)
Boiling Point333.35°C (rough estimate)
Density1.2319 (rough estimate)
AppearanceYellow Crystalline Solid
Coloroff-white
Formpowder
Water Solubilityinsoluble
Refractive Index1.6000 (estimate)
Log P3.114 (est)

Safety & Handling

Warning GHS07 GHS09 Hazard Statements H302 Harmful if swallowed H315 Causes skin irritation H319 Causes serious eye irritation H335 May cause respiratory irritation H400 Very toxic to aquatic life H410 Very toxic to aquatic life with long lasting effects Precautionary Statements P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P264 Wash … thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P271 Use only outdoors or in a well-ventilated area. P273 Avoid release to the environment. P280 Wear protective gloves/protective clothing/eye protection/face protection. P319 Get medical advice/attention if you feel unwell. P321 Specific treatment (see … on this label). P330 Rinse mouth. P391 Collect spillage. P405 Store locked up. P501 Dispose of contents/container in accordance with local regulations. P264+P265 Wash … thoroughly after handling. P301+P317 Get emergency medical help. P302+P352 IF ON SKIN: Wash with plenty of water. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P332+P317 Get emergency medical help. P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P403+P233 Store in a well-ventilated place. Keep container tightly closed. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29329900
Storage Class11 - Combustible Solids
WGK (Germany)3

Other Names

Prunetol | Genisteol | Differenol A | 574'-Trihydroxyisoflavone | 57-dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one | 4'57-trihydroxyisoflavone | 57-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one

Related Products

Chemical Properties

CAS Number
446-72-0
EC Number
207-174-9
Mol. Weight
270.24
HS Code
29329900

Industries

Documentation