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Flavors & Fragrances

Resveratrol

CAS: 501-36-0

Overview

Resveratrol (CAS 501-36-0 ) is a naturally derived polyphenol sourced primarily from Japanese knotweed and grape-derived materials. It functions as an antioxidant active across nutraceutical, cosmetic, and pharmaceutical formulations.

Buyers source it as a standardized botanical extract or as a highly purified synthetic equivalent depending on application requirements. In dietary supplements, it is formulated into capsules, tablets, and softgels.

These products target antioxidant and longevity-positioned product lines. Cosmetic formulators incorporate it into anti-aging serums, creams, and facial treatments where it provides antioxidant protection for the skin matrix.

It supports UV-induced oxidative stress mitigation in various topical applications. Food and beverage manufacturers use it as a functional ingredient in fortified products where clean-label positioning is relevant.

Pharmaceutical researchers and contract manufacturers also source high-purity grades for use in investigational formulations. It is also utilized in standardized reference applications across the global industry.

The material is supplied as a white to off-white crystalline powder. Standard grades include 98%+ purity (HPLC) for pharmaceutical and nutraceutical use, with food-grade and cosmetic-grade specifications available.

Suppliers ensure compliance with international quality standards such as USP , FCC , and Ph.Eur. to meet regulatory needs. Botanical extract forms are commonly offered alongside synthetic high-purity material.

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Physical Properties

Melting Point254 °C
Boiling Point449.1±14.0 °C(Predicted)
Density1.359±0.06 g/cm3(Predicted)
AppearanceOff-White to Tan Powder
ColorOff-white
FormPowder
Water SolubilitySoluble in water (3 mg/100mL), ethanol (50 mg/mL), DMSO (16 mg/mL), DMF (~65 mg/mL), PBS (pH 7.2) (~100µg/mL), methanol, and acetone (50 mg/mL).
Log P3.139 (est)

Safety & Handling

Danger GHS05 GHS07 Hazard Statements H315 Causes skin irritation H318 Causes serious eye damage H319 Causes serious eye irritation H335 May cause respiratory irritation Precautionary Statements P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P264 Wash … thoroughly after handling. P271 Use only outdoors or in a well-ventilated area. P280 Wear protective gloves/protective clothing/eye protection/face protection. P317 Get emergency medical help. P319 Get medical advice/attention if you feel unwell. P321 Specific treatment (see … on this label). P405 Store locked up. P501 Dispose of contents/container in accordance with local regulations. P264+P265 Wash … thoroughly after handling. P302+P352 IF ON SKIN: Wash with plenty of water. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P332+P317 Get emergency medical help. P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P403+P233 Store in a well-ventilated place. Keep container tightly closed. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P305+P354+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29072900
Storage Class11 - Combustible Solids
WGK (Germany)3

Other Names

5-[(E)-2-(4-hydroxyphenyl)vinyl]benzene-13-diol | 354'-trihydroxystilbene | 34'5-trihydroxystilbene | 34'5-trihydroxy-trans-stilbene | 34'5-stilbenetriol | (E)-resveratrol | trans-resveratrol | Resvida

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Chemical Properties

CAS Number
501-36-0
EC Number
610-504-8
Mol. Weight
228.24
HS Code
29072900

Industries

Documentation