Overview
Bisabolol (CAS 515-69-5 ), also known as α-Bisabolol, is a naturally derived monocyclic sesquiterpene alcohol originally sourced from German chamomile. It is now predominantly produced synthetically or from candeia tree oil for industrial use.
It functions as a skin-conditioning agent and active carrier in cosmetic and pharmaceutical formulations. This ingredient is highly valued for its ability to enhance the penetration of other actives into the skin layers.
In skincare formulations, it is used as a primary soothing and moisturizing agent in creams, serums, and lotions. These products typically target sensitive or reactive skin types requiring gentle care.
Its carrier properties make it a preferred solvent for active ingredients in topical pharmaceutical preparations. This includes wound-care products and medicated creams where high purity and efficacy are essential.
Fragrance formulators incorporate it as a fixative and mild floral base note in fine fragrances and functional perfumery. It also appears in after-sun products, baby care lines, and anti-aging formulations.
The material is supplied as a clear to pale yellow viscous liquid. Standard commercial grades include natural and synthetic variants, with natural-origin material often certified to differentiate supply chains.
Cosmetic-grade and pharmaceutical-grade specifications are both available to meet industry needs. Natural grades are commonly accompanied by optical purity data confirming the specific enantiomer content.
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Physical Properties
| Melting Point | <25 °C |
| Boiling Point | 155-157 °C @ Press: 12 Torr |
| Density | 0.9211 g/cm³ @ Temp: 20 °C |
| Flash Point | 135°C |
| Appearance | colourless to faintly yellow viscous liquid |
| Color | Clear Colourless |
| Odor | at 100.00 %. mild floral peppery balsamic clean |
| Form | Liquid |
| Water Solubility | Soluble in alcohol, natural, mineral and synthetic oils. Insoluble in water. |
| Refractive Index | n 20/D 1.496 |
| Log P | 5.63 |
Safety & Handling
Warning GHS07 GHS09 Hazard Statements H317 May cause an allergic skin reaction H411 Toxic to aquatic life with long lasting effects Precautionary Statements P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P272 Contaminated work clothing should not be allowed out of the workplace. P273 Avoid release to the environment. P280 Wear protective gloves/protective clothing/eye protection/face protection. P321 Specific treatment (see … on this label). P391 Collect spillage. P501 Dispose of contents/container in accordance with local regulations. P302+P352 IF ON SKIN: Wash with plenty of water. P333+P317 Get emergency medical help. P362+P364 Take off contaminated clothing and wash it before reuse.
Trade & Regulatory
| HS Code | 29061900 |
| WGK (Germany) | 2 |
Other Names
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Chemical Properties
- CAS Number
- 515-69-5
- EC Number
- 208-205-9
- Mol. Weight
- 222.37
- HS Code
- 29061900
- Category
- Oils, Fats & Waxes