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Heterocyclic Compounds

20-Hydroxyecdysone

CAS: 5289-74-7

Overview

20-Hydroxyecdysone (CAS 5289-74-7 ), also known as beta-Ecdysone or 20E, is a naturally occurring phytoecdysteroid extracted primarily from plants such as Cyanotis arachnoidea and Leuzea carthamoides.

In commercial markets, it functions as a bioactive ingredient targeting protein synthesis support, skin conditioning, and adaptogenic formulation development for various industrial applications.

In sports nutrition and dietary supplements, 20E is incorporated into capsule and powder formulations positioned around muscle recovery and physical performance. Cosmetic formulators use it in anti-aging topicals.

Its conditioning activity supports product claims around elasticity and cellular renewal in skin-firming products. Pharmaceutical researchers source 20E as a reference standard for metabolic research.

It is also used as an active ingredient candidate for anabolic research programs. In functional food development, it appears in standardized plant extracts blended into protein powders and energy bars.

20-Hydroxyecdysone is supplied as a white to off-white crystalline powder, both as isolated pure compound and as standardized plant extracts with defined 20E content typically 95%+ by HPLC.

Common supply grades include research-grade, cosmetic-grade, and food/nutraceutical-grade material. Standardized extracts are also available at lower concentrations for direct use in supplement manufacturing.

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Physical Properties

Melting Point239-240 °C
Boiling Point498.63°C (rough estimate)
Density1.0760 (rough estimate)
Colorwhite
Formpowder
Refractive Index1.5800 (estimate)
Log P-0.270 (est)

Safety & Handling

Warning GHS09 Hazard Statements H400 Very toxic to aquatic life H410 Very toxic to aquatic life with long lasting effects Precautionary Statements P273 Avoid release to the environment. P391 Collect spillage. P501 Dispose of contents/container in accordance with local regulations.

Trade & Regulatory

HS Code29372900
WGK (Germany)2

Other Names

beta-Ecdysone | THE-7 | Cholest-7-en-6-one2314202225-hexahydroxy-(2β22R)- | 5β-Cholest-7-en-6-one14202225-hexahydroxy-(22R)- | 5β-Cholest-7-en-6-one142022β25-hexahydroxy- | (2β22R)-2314202225-Hexahydroxycholest-7-en-6-one | CYANOTIS ARACHNOIDEA ROOT EXTRACT | 20E

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Chemical Properties

CAS Number
5289-74-7
EC Number
811-097-1
Mol. Weight
480.6
HS Code
29372900

Industries

Documentation