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alpha-D-glucose pentaacetate

CAS: 604-68-2

Overview

Alpha-D-glucose pentaacetate (CAS 604-68-2 ), also known as pentaacetyl-alpha-D-glucose, is a fully acetylated glucose derivative used primarily as a pharmaceutical intermediate and specialty chemical in fine chemical synthesis.

It serves as a protected glucose building block, enabling selective glycosylation reactions without the need for additional protection steps. In pharmaceutical manufacturing, it functions as a key starting material for synthesis.

This compound is used for synthesizing nucleoside analogues, glycosylated drug compounds, and other carbohydrate-based active pharmaceutical ingredients. Its well-defined anomeric configuration makes it the preferred precursor for stereoselective glycosylation.

This precision is critical to API purity and regulatory compliance. In personal care formulations, it is evaluated as a stabilizing and moisturizing agent where controlled release of glucose moieties supports skin conditioning performance.

Research and specialty chemical producers also use it as a reference standard or reagent-grade intermediate in carbohydrate chemistry workflows. It is supplied as a white to off-white crystalline powder for various uses.

It is available in reagent-grade and pharmaceutical-grade specifications to meet the purity requirements of API synthesis and GMP-compliant manufacturing environments. Packaging typically ranges from laboratory-scale quantities up to bulk orders.

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Physical Properties

Melting Point113.3 °C
Boiling Point~0.115 °C (approx) @ Press: 3 x 10-4 Torr
Density1.3984 (rough estimate)
Appearancewhite to light yellow crystal powde
ColorWhite to off-white
Odorat 100.00 %. odorless
FormPowder
Water Solubility< 5 G/L (25 ºC)
Vapor Pressure0-0Pa at 20-50℃
Refractive Index105.5 ° (C=1.5, MeOH)
Log P1.87 at 25℃ and pH5.7

Safety & Handling

Warning GHS07 Hazard Statements H302 Harmful if swallowed H317 May cause an allergic skin reaction Precautionary Statements P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P264 Wash … thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P272 Contaminated work clothing should not be allowed out of the workplace. P280 Wear protective gloves/protective clothing/eye protection/face protection. P321 Specific treatment (see … on this label). P330 Rinse mouth. P501 Dispose of contents/container in accordance with local regulations. P301+P317 Get emergency medical help. P302+P352 IF ON SKIN: Wash with plenty of water. P333+P317 Get emergency medical help. P362+P364 Take off contaminated clothing and wash it before reuse.

Trade & Regulatory

HS Code29224210
Storage Class11 - Combustible Solids
WGK (Germany)3

Other Names

alpha-D-Glucopyranosepentaacetate | Pentaacetyl-alpha-D-glucose | 12346-Penta-O-acetyl-alpha-D-glucopyranose | Penta-O-acetyl-alpha-D-glucopyranose | 1CS424NS93 | α-D-Glucopyranose12346-pentaacetate | Glucopyranosepentaacetateα-D- | α-D-Glucopyranosepentaacetate

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Chemical Properties

CAS Number
604-68-2
EC Number
210-073-2
Mol. Weight
390.34
HS Code
29224210

Industries

Documentation