Overview
Alpha-D-glucose pentaacetate (CAS 604-68-2 ), also known as pentaacetyl-alpha-D-glucose, is a fully acetylated glucose derivative used primarily as a pharmaceutical intermediate and specialty chemical in fine chemical synthesis.
It serves as a protected glucose building block, enabling selective glycosylation reactions without the need for additional protection steps. In pharmaceutical manufacturing, it functions as a key starting material for synthesis.
This compound is used for synthesizing nucleoside analogues, glycosylated drug compounds, and other carbohydrate-based active pharmaceutical ingredients. Its well-defined anomeric configuration makes it the preferred precursor for stereoselective glycosylation.
This precision is critical to API purity and regulatory compliance. In personal care formulations, it is evaluated as a stabilizing and moisturizing agent where controlled release of glucose moieties supports skin conditioning performance.
Research and specialty chemical producers also use it as a reference standard or reagent-grade intermediate in carbohydrate chemistry workflows. It is supplied as a white to off-white crystalline powder for various uses.
It is available in reagent-grade and pharmaceutical-grade specifications to meet the purity requirements of API synthesis and GMP-compliant manufacturing environments. Packaging typically ranges from laboratory-scale quantities up to bulk orders.
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Physical Properties
| Melting Point | 113.3 °C |
| Boiling Point | ~0.115 °C (approx) @ Press: 3 x 10-4 Torr |
| Density | 1.3984 (rough estimate) |
| Appearance | white to light yellow crystal powde |
| Color | White to off-white |
| Odor | at 100.00 %. odorless |
| Form | Powder |
| Water Solubility | < 5 G/L (25 ºC) |
| Vapor Pressure | 0-0Pa at 20-50℃ |
| Refractive Index | 105.5 ° (C=1.5, MeOH) |
| Log P | 1.87 at 25℃ and pH5.7 |
Safety & Handling
Warning GHS07 Hazard Statements H302 Harmful if swallowed H317 May cause an allergic skin reaction Precautionary Statements P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P264 Wash … thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P272 Contaminated work clothing should not be allowed out of the workplace. P280 Wear protective gloves/protective clothing/eye protection/face protection. P321 Specific treatment (see … on this label). P330 Rinse mouth. P501 Dispose of contents/container in accordance with local regulations. P301+P317 Get emergency medical help. P302+P352 IF ON SKIN: Wash with plenty of water. P333+P317 Get emergency medical help. P362+P364 Take off contaminated clothing and wash it before reuse.
Trade & Regulatory
| HS Code | 29224210 |
| Storage Class | 11 - Combustible Solids |
| WGK (Germany) | 3 |
Other Names
Related Products
Chemical Properties
- CAS Number
- 604-68-2
- EC Number
- 210-073-2
- Mol. Weight
- 390.34
- HS Code
- 29224210
- Category
- Oils, Fats & Waxes