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Alcohols & Glycols

Panthenyl ethyl ether

CAS: 667-83-4

Overview

Panthenyl ethyl ether (CAS 667-83-4 ) is a lipophilic derivative of provitamin B5, modified to improve skin penetration compared to standard panthenol. It functions as a moisturizing and conditioning active in cosmetic and pharmaceutical topical formulations.

In leave-on skincare products such as serums, creams, and lotions, it delivers sustained hydration while supporting the skin barrier. This makes it particularly suitable for sensitive and dry skin formulations.

Hair care formulators use it in conditioners and styling products where its enhanced lipophilicity improves deposition on the hair shaft. This characteristic helps to significantly reduce moisture loss in hair treatments.

It is incorporated into topical pharmaceutical preparations requiring a provitamin B5 source with improved penetration through lipid-rich skin layers. This ensures the active reaches deeper layers of the dermis effectively.

Suncare and after-sun products also use it for its moisture-retention profile alongside UV-protective actives. It helps soothe the skin and restore hydration levels after exposure to environmental stressors.

Panthenyl ethyl ether is supplied as a clear to slightly yellowish liquid. It is available in cosmetic-grade specification, the standard form for personal care and topical pharmaceutical applications.

Packaging typically ranges from small drums to bulk quantities suited to industrial formulation volumes. This ensures flexibility for both boutique manufacturers and large-scale industrial production facilities.

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Physical Properties

Boiling Point443.8±45.0 °C(Predicted)
Density1.073 g/mL at 20 °C(lit.)
Flash Point110 °C

Other Names

(2R)-N-(3-ethoxypropyl)-24-dihydroxy-33-dimethylbutanamide | (+)-N-(3-ethoxypropyl)-24-dihydroxy-33-dimethylbutyramide | F4WMF8NX3B | ORISTAR PEE | RITAPAN EE | (+)-PANTOTHENYL ETHYL ETHER | ButanamideN-(3-ethoxypropyl)-24-dihydroxy-33-dimethyl-(2R)- | RefChem:858491

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Chemical Properties

CAS Number
667-83-4
EC Number
211-569-1
Mol. Weight
233.30

Industries

Documentation