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Amino Acids & Peptides

Dexpanthenol

CAS: 81-13-0

Overview

Dexpanthenol (CAS 81-13-0 ), also known as pantothenyl alcohol and D-pantothenol, is the biologically active alcohol analogue of pantothenic acid (vitamin B5). In both pharmaceutical and personal care manufacturing, it functions as a humectant and skin-conditioning agent.

This pro-vitamin converts to pantothenic acid upon absorption into the skin or hair. In topical pharmaceutical formulations, it is the active ingredient in wound-healing creams, nasal sprays, and eye drops, where it supports epithelial repair and tissue regeneration.

Cosmetic formulators incorporate it into shampoos, conditioners, and leave-in treatments to improve hair fiber moisture retention and reduce breakage. Skin care products such as lotions, serums, and barrier creams use it to deliver sustained hydration.

The ingredient supports the skin's natural recovery process and is frequently used in baby care products. It also appears in post-procedure skincare lines where a well-tolerated, efficacious moisturizing active is required for sensitive skin.

Dexpanthenol is supplied as a viscous liquid, typically at 75% or 98%+ concentrations. Pharmaceutical-grade material is available to USP , BP , and Ph. Eur. specifications for high-purity manufacturing requirements.

Cosmetic-grade material is also commonly offered for personal care applications. Bulk supply is standard in drums or IBCs, with smaller quantities available for development and QA purposes to meet various production scales.

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Physical Properties

Melting Point<25 °C
Boiling Point118-120 °C @ Press: 0.02 Torr
Density1.2 g/cm³ @ Temp: 20 °C
Flash Point118-120°C/0.02m
Appearanceclear colorless to slightly yellow viscous liquid
ColorClear colorless to slightly yellow
FormViscous Liquid or Semi Solid
Water Solubilitysoluble
Vapor Pressure0Pa at 25℃
Refractive Index1.495-1.502
pHpH (100g/l,25℃) : 8.5~10.5
Log P-1.06 at 22℃

Trade & Regulatory

HS Code29241990
Storage Class10 - Combustible liquids
WGK (Germany)1

Other Names

pantothenyl alcohol | D(+)-panthenol | D-pantothenyl alcohol | D-pantothenol | (2R)-24-dihydroxy-N-(3-hydroxypropyl)-33-dimethylbutanamide | (+)-panthenol | Bepanthen | Ilopan

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Chemical Properties

CAS Number
81-13-0
EC Number
201-327-3
Mol. Weight
205.25
HS Code
29241990

Industries

Documentation