Overview
Disulfiram (CAS 97-77-8 ), also known commercially as Tetraethylthiuram Disulfide or TETD, is an organosulfur compound with established roles across rubber manufacturing and pharmaceutical production.
It functions primarily as a vulcanization accelerator, biocide, and active pharmaceutical ingredient precursor. In rubber and polymer processing, it acts as an ultra-fast vulcanization accelerator for various applications.
This compound enables rapid crosslinking in latex and dry rubber compounds used in gloves, seals, and industrial goods. Pharmaceutical manufacturers source it as an API or intermediate for alcohol-aversion therapy formulations.
Consistent purity and specification compliance are critical to regulatory approval in these medical contexts. As an industrial biocide and antifungal agent, it is incorporated into preservation systems for coatings and adhesives.
It is also used in agricultural products and functions as an antioxidant stabilizer in certain polymer formulations. This protects materials against oxidative degradation during both processing and long-term storage.
The product is supplied as a white to off-white crystalline powder. Standard grades include technical-grade material for rubber and industrial applications, alongside pharmaceutical-grade product meeting USP and BP specifications.
Bulk quantities are available for industrial buyers, with pharmaceutical-grade material typically subject to stricter documentation. These high-purity grades ensure safety and efficacy for medicinal use and specialized chemical synthesis.
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Physical Properties
| Melting Point | 71.5 °C |
| Boiling Point | 117 °C @ Press: 17 Torr |
| Density | 1.30 g/cm³ |
| Flash Point | 117°C/17mm |
| Appearance | yellow-white crystals or grey powder |
| Color | Light yellow |
| Odor | lt. gray powd., sl. odor |
| Form | Crystals, Crystalline Powder or Granules |
| Water Solubility | 0.02 g/100 mL |
| Vapor Pressure | 0Pa at 25℃ |
| Refractive Index | 1.5500 (estimate) |
| Log P | 3.6 at 21℃ |
Safety & Handling
Warning GHS07 GHS08 GHS09 Hazard Statements H302 Harmful if swallowed H303 May be harmful if swallowed H317 May cause an allergic skin reaction H319 Causes serious eye irritation H320 Causes eye irritation H332 Harmful if inhaled H341 Suspected of causing genetic defects H361 Suspected of damaging fertility or the unborn child H370 Causes damage to organs H372 Causes damage to organs through prolonged or repeated exposure H373 May causes damage to organs through prolonged or repeated exposure H400 Very toxic to aquatic life H410 Very toxic to aquatic life with long lasting effects H302+H332 Harmful if swallowed or if inhaled Precautionary Statements P203 Obtain, consult and follow expert instructions for use. P260 Do not breathe dust/fume/gas/mist/vapours/spray. P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P264 Wash … thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P271 Use only outdoors or in a well-ventilated area. P272 Contaminated work clothing should not be allowed out of the workplace. P273 Avoid release to the environment. P280 Wear protective gloves/protective clothing/eye protection/face protection. P317 Get emergency medical help. P318 IF exposed or concerned, get medical advice. P319 Get medical advice/attention if you feel unwell. P321 Specific treatment (see … on this label). P330 Rinse mouth. P391 Collect spillage. P405 Store locked up. P501 Dispose of contents/container in accordance with local regulations. P264+P265 Wash … thoroughly after handling. P301+P317 Get emergency medical help. P302+P352 IF ON SKIN: Wash with plenty of water. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P308+P316 Get emergency medical help immediately. P333+P317 Get emergency medical help. P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Trade & Regulatory
| HS Code | 29303000 |
| UN Number | 3077 |
| ADR Class | 9 |
| Packing Group | III |
| WGK (Germany) | 3 |
Other Names
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Chemical Properties
- CAS Number
- 97-77-8
- EC Number
- 202-607-8
- Mol. Weight
- 296.5
- HS Code
- 29303000
- Category
- Flavors & Fragrances