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Heterocyclic Compounds

4-cyanopyridine

CAS: 100-48-1

Overview

4-Cyanopyridine (CAS 100-48-1 ), also known as isonicotinic acid nitrile and abbreviated as 4-CP, is a pyridine-based nitrile building block used across pharmaceutical synthesis and specialty chemical manufacturing.

It functions primarily as a reactive intermediate, enabling the construction of more complex heterocyclic structures through its dual nitrile and pyridine functionalities in various chemical processes.

In pharmaceutical manufacturing, 4-CP is a key precursor in the synthesis of antifungal agents, antivirals, and other nitrogen-containing active pharmaceutical ingredients for the global market.

It is used in the production of ligands and coordination complexes that serve as catalysts or catalyst precursors in organometallic chemistry and advanced material science applications.

Agrochemical formulators use it as a building block for pyridine-derived herbicides and fungicides. In flavor chemistry, isonicotinic acid nitrile contributes to select fragrance and flavor compound synthesis.

This is particularly useful where pyridine-ring structures are required. 4-Cyanopyridine is supplied as a white to off-white crystalline solid for industrial and laboratory use.

Standard commercial grades include technical and high-purity specifications suitable for pharmaceutical intermediate and research applications. Packaging typically ranges from kilogram-scale to bulk orders.

Our supply chain ensures consistent quality for multi-hundred kilogram bulk orders for industrial synthesis. We maintain strict adherence to safety and handling protocols for all chemical shipments.

Contact us for supply of 4-cyanopyridine

Physical Properties

Melting Point79 °C
Boiling Point78 °C @ Press: 6 Torr
Density1.1145 (rough estimate)
Flash Point88 °C
AppearanceThe cyanopyridines are as follows: 2-cyano-: A white to tan liquid or solid. Almond odor. Boiling point=2213℃ ; freezing/melting point=27℃ ; flash point=89℃ . 3-cyano-: a colorless liquid or gray crystal- line solid.
ColorWhite to off-white
FormCrystals or Powder
Water Solubility3.2 g/100ml (16.4 ºC)
Vapor Pressure41.9Pa at 25℃
Refractive Index1.5242 (estimate)
Log P0.46 at 25℃

Safety & Handling

Warning GHS07 Hazard Statements H302 H302 H312 H312 H319 H319 H332 H332 Precautionary Statements P261 P261 P264 P264 P270 P270 P271 P271 P280 P280 P317 P317 P321 P321 P330 P330 P501 P501 P264+P265 P264+P265 P301+P317 P301+P317 P302+P352 P302+P352 P304+P340 P304+P340 P337+P317 P337+P317 P362+P364 P362+P364 P305+P351+P338 P305+P351+P338

Trade & Regulatory

HS Code29333999
Storage Class11 - Combustible Solids
WGK (Germany)3

Other Names

4-Pyridinecarbonitrile | pyridine-4-carbonitrile | Isonicotinic acid nitrile | BY3226D010 | γ-Cyanopyridine | p-Cyanopyridine | 4-CP

Related Products

Chemical Properties

CAS Number
100-48-1
EC Number
202-856-7
Mol. Weight
104.11
HS Code
29333999

Industries

Documentation