Overview
Glutaric acid (CAS 110-94-1 ), also known commercially as glutarate, is a five-carbon dicarboxylic acid used across pharmaceutical, cosmetic, and food applications as a pH buffer, acidulant, and reactive intermediate.
Its bifunctional acid structure makes it a practical building block for synthesis and a reliable acidifying agent in formulated products. In pharmaceutical manufacturing, it functions as a co-former in active pharmaceutical ingredient salt development.
This material is essential for cocrystal development, improving solubility and stability profiles of drug candidates. Personal care formulators incorporate it as a mild acidulant and buffering agent in skin care products.
Controlled pH levels directly affect preservative efficacy and product shelf life in cosmetic formulations. In food and flavoring applications, it contributes a clean, mild acidic note and supports preservation in processed food systems.
It also serves as a precursor in the synthesis of polyesters, plasticizers, and specialty polymers used across industrial coating and resin formulations. The product is supplied as a white crystalline powder for easy handling.
Food-grade and pharmaceutical-grade material is available, with the latter typically conforming to USP or BP specifications. Technical-grade material is also offered for industrial synthesis and polymer applications.
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Physical Properties
| Melting Point | 97.5-98 °C |
| Boiling Point | 200 °C @ Press: 20 Torr |
| Density | 1.429 g/cm³ @ Temp: 15 °C |
| Flash Point | 200°C/20mm |
| Appearance | white or off-white crystals |
| Color | Orange |
| Form | Crystalline Powder |
| Water Solubility | 430 g/L (20 ºC) |
| Vapor Pressure | 0.022 hPa (18.5 °C) |
| Refractive Index | nD106 1.41878 |
| pH | 3.7(1 mM solution);3.17(10 mM solution);2.66(100 mM solution) |
| Log P | -0.26 at 25℃ |
Safety & Handling
Danger GHS05 GHS07 Hazard Statements H314 Causes severe skin burns and eye damage H318 Causes serious eye damage H319 Causes serious eye irritation Precautionary Statements P260 Do not breathe dust/fume/gas/mist/vapours/spray. P264 Wash … thoroughly after handling. P280 Wear protective gloves/protective clothing/eye protection/face protection. P316 Get emergency medical help immediately. P317 Get emergency medical help. P321 Specific treatment (see … on this label). P363 Wash contaminated clothing before reuse. P405 Store locked up. P501 Dispose of contents/container in accordance with local regulations. P264+P265 Wash … thoroughly after handling. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help. P301+P330+P331 Rinse mouth. Do NOT induce vomiting. P302+P361+P354 IF ON SKIN: Take off immediately all contaminated clothing. Rinse skin with water/shower. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P305+P354+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Trade & Regulatory
| HS Code | 29171990 |
| Storage Class | 8A - Combustible corrosive hazardous materials |
| WGK (Germany) | 1 |
Other Names
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Chemical Properties
- CAS Number
- 110-94-1
- EC Number
- 203-817-2
- Mol. Weight
- 132.11
- HS Code
- 29171990
- Category
- Catalysts & Catalyst Precursors