Overview
Dimethylglycine (CAS 1118-68-9 ), commonly abbreviated as DMG, is a naturally occurring amino acid derivative used across pharmaceutical, cosmetic, and biotechnology applications. It functions as a buffering agent, chelator, and humectant.
This versatile compound supports formulation stability and active ingredient performance in finished products. In pharmaceutical and nutraceutical manufacturing, DMG serves as a precursor compound and pH buffer in various delivery systems.
It is frequently utilized in tablet, capsule, and liquid formulations requiring precise acid-base control. Cosmetic formulators incorporate it into moisturizing creams, serums, and skin-conditioning products to enhance texture.
Its humectant properties support water retention in the skin matrix, making it a valuable additive for personal care. Biotechnology and cell culture applications rely on DMG as a chelating agent to sequester metal ions.
This sequestration prevents interference with assay accuracy or cell viability during sensitive laboratory processes. It also appears in topical and oral healthcare formulations where controlled buffering capacity is a critical quality parameter.
Dimethylglycine is commercially available as a white crystalline powder for industrial use. Standard supply grades include pharmaceutical-grade ( USP / BP -compliant) and technical-grade material for diverse manufacturing needs.
Food-grade and research-grade specifications are also available from select suppliers to meet specific regulatory demands. Bulk quantities are typically offered in kilogram and metric-ton packaging for commercial production.
These packaging options are designed to meet both development-scale requirements and large-scale commercial manufacturing. The material maintains high stability when stored under recommended industrial conditions.
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Physical Properties
| Melting Point | 182-183 °C |
| Boiling Point | 193.35°C (rough estimate) |
| Density | 1 g/cm 3 |
| Appearance | white to slightly yellow crystalline powder |
| Color | White to slightly yellow |
| Form | Crystalline Powder |
| Water Solubility | soluble |
| Refractive Index | 1.4674 (estimate) |
Safety & Handling
Warning GHS07 Hazard Statements H302 H302 Precautionary Statements P264 P264 P270 P270 P330 P330 P501 P501 P301+P317 P301+P317
Trade & Regulatory
| HS Code | 29224999 |
| Storage Class | 11 - Combustible Solids |
| WGK (Germany) | 3 |
Other Names
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Chemical Properties
- CAS Number
- 1118-68-9
- EC Number
- 214-267-8
- Mol. Weight
- 103.12
- HS Code
- 29224999
- Category
- Amino Acids & Peptides