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Pharmaceutical Intermediates

Dimethylhydantoin

CAS: 77-71-4

Overview

Dimethylhydantoin ( CAS 77-71-4 ), commercially known as DMH or Dantoin DMH, is a cyclic urea derivative used across pharmaceutical, personal care, and specialty chemical manufacturing. It functions primarily as a building block for active intermediates.

The compound acts as a buffering agent and a precursor in biocide synthesis. In personal care formulations, DMH is the backbone of DMDM hydantoin, a widely produced preservative system used in shampoos and skin care products.

Pharmaceutical manufacturers use it as an intermediate in synthesizing hydantoin-derived APIs, where its ring structure enables controlled chemical modification. This versatility makes it essential for various medical applications.

In industrial water treatment and antimicrobial formulations, DMH serves as a precursor to halogenated hydantoins. These are chlorine- and bromine-releasing biocides used in cooling towers and pool sanitation systems.

Specialty chemical producers also use it as a pH buffer in reaction systems requiring stable mildly acidic conditions. This ensures consistent results during complex chemical manufacturing processes and industrial reactions.

Dimethylhydantoin is supplied as a white crystalline powder. Technical grade is the standard commercial form, with pharmaceutical-grade material available for API synthesis and regulated applications requiring high purity.

Bulk quantities are typically offered in multi-kilogram bags or fiber drums. Smaller packaging is also available for laboratory and development use to meet the specific needs of research facilities and small-scale production.

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Physical Properties

Melting Point178 °C
Boiling Point237.54°C (rough estimate)
Density1.261 g/cm³
Flash Point193°C
Appearancewhite to off-white crystals or crystalline powder
ColorWhite to off-white
FormCrystalline Powder or Crystals
Water Solubilitysoluble
Refractive Index1.4730 (estimate)
Log P-0.480

Trade & Regulatory

HS Code29332100
Storage Class11 - Combustible Solids
WGK (Germany)2

Other Names

55-DIMETHYLHYDANTOIN | 24-Imidazolidinedione55-dimethyl- | Dantoin DMH | 55-Dimethyl-24-imidazolidinedione | Dantoin 736 | Hydantoin55-dimethyl- | DM HYDANTOIN | DMH

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Chemical Properties

CAS Number
77-71-4
EC Number
201-051-3
Mol. Weight
128.13
HS Code
29332100

Industries

Documentation