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Amino Acids & Peptides

Tranexamic acid

CAS: 1197-18-8

Overview

Tranexamic acid (CAS 1197-18-8 ), also known as trans-AMCHA, is a synthetic lysine derivative used across pharmaceutical and cosmetic manufacturing. It functions as a plasmin inhibitor in drug formulations and as a skin-brightening active in topical cosmetic products.

In pharmaceutical manufacturing, this compound is the active ingredient in antifibrinolytic drug products such as tablets, injectables, and oral solutions. These formulations are primarily indicated for managing heavy bleeding in various clinical settings.

Cosmetic formulators incorporate the material into serums, creams, and spot-treatment products targeting hyperpigmentation, melasma, and uneven skin tone. It is used as a key active in OTC brightening formulations where melanin synthesis inhibition is the targeted mechanism.

Contract manufacturers and finished-goods brands source it as a pharmaceutical intermediate for both prescription and consumer-facing product lines. This versatility makes it a staple ingredient for diverse industrial applications and specialized chemical processing.

The material is supplied as a white crystalline powder and is available in USP , BP , and Ph. Eur. grades for pharmaceutical applications. Cosmetic-grade material is also offered specifically for personal care use and topical product development.

Bulk quantities are standard for industrial buyers, with smaller quantities available for formulation development and pilot testing. Our supply chain ensures consistent quality and compliance with international regulatory standards for every batch delivered.

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Physical Properties

Melting Point>300 °C
Boiling Point281.88°C (rough estimate)
Density1.0806 (rough estimate)
Appearancewhite crystalline powder
ColorWhite
FormCrystalline Powder
Water Solubility1g/6ml
Vapor Pressure1.72hPa at 25℃
Refractive Index1.4186 (estimate)

Safety & Handling

Warning GHS07

Trade & Regulatory

HS Code29224999
WGK (Germany)2

Other Names

trans-Tranexamic acid | trans-Amcha | trans-4-Aminomethylcyclohexane-1-carboxylic acid | trans-4-(Aminomethyl)cyclohexanecarboxylic acid | Tranhexamic acid | Tranexmic acid | Femstrual® | Cyklokapron®

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Chemical Properties

CAS Number
1197-18-8
EC Number
214-818-2
Mol. Weight
157.21
HS Code
29224999

Industries

Documentation