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Amino Acids & Peptides

Oxaceprol

CAS: 33996-33-7

Overview

Oxaceprol (CAS 33996-33-7 ), also known by the trade name Jonctum and commercially as acetyl hydroxyproline, is a modified amino acid derivative used in pharmaceutical and cosmetic formulations.

It functions as a humectant, antioxidant stabilizer, and pH-buffering agent, supporting both skin conditioning and active ingredient performance in finished products for various industries.

In pharmaceutical preparations, it has been developed as an active ingredient in anti-inflammatory and joint-support formulations, particularly for oral and topical dosage forms targeting connective tissue.

Cosmetic formulators incorporate it into premium skincare products, such as serums, creams, and masks, where its moisture-retention capacity supports essential skin hydration claims.

Its buffering behavior helps stabilize pH-sensitive formulations, making it relevant for developers working with peptide-based or enzyme-active systems in modern laboratory settings.

The compound also appears in functional topical preparations where collagen-pathway support is a desired positioning attribute for high-end personal care and dermatological brands.

This material is supplied as a white to off-white crystalline powder. It is available in pharmaceutical-grade specifications suited to drug product manufacturing and cosmetic-grade material.

Buyers should confirm purity levels and documentation, including COA and relevant pharmacopoeial alignment, when sourcing for regulated end uses in global chemical markets.

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Physical Properties

Melting Point132 °C
Boiling Point303.8°C (rough estimate)
Density1.3346 (rough estimate)
ColorWhite
FormCrystalline Powder
Vapor Pressure0Pa at 20℃
Refractive Index1.4490 (estimate)
Log P-1.51 at 20℃

Safety & Handling

Danger GHS05 GHS07 Hazard Statements H315 H315 H318 H318 H335 H335 Precautionary Statements P261 P261 P264 P264 P271 P271 P280 P280 P317 P317 P319 P319 P321 P321 P405 P405 P501 P501 P264+P265 P264+P265 P302+P352 P302+P352 P304+P340 P304+P340 P332+P317 P332+P317 P362+P364 P362+P364 P403+P233 P403+P233 P305+P354+P338 P305+P354+P338

Trade & Regulatory

HS Code29339900
Storage Class11 - Combustible Solids
WGK (Germany)3

Other Names

(2S4R)-1-acetyl-4-hydroxypyrrolidine-2-carboxylic acid | Jonctum | acetyl hydroxyproline | N-Acetylhydroxyproline | Q0XV76B96L | (-)-1-Acetyl-4-hydroxy-L-proline | L-Proline1-acetyl-4-hydroxy-(4R)- | L-Proline1-acetyl-4-hydroxy-trans-

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Chemical Properties

CAS Number
33996-33-7
EC Number
251-780-6
Mol. Weight
173.17
HS Code
29339900

Industries

Documentation