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Pharmaceutical Intermediates

Ascorbyl glucoside

CAS: 129499-78-1

Overview

Ascorbyl glucoside (CAS 129499-78-1 ), commercially known as AA-2G, is a stable, glycosylated form of vitamin C used across cosmetic, pharmaceutical, and food applications. Unlike free ascorbic acid, it resists oxidative degradation under normal formulation and storage conditions.

The compound releases active vitamin C enzymatically upon skin or biological contact. This stability profile makes it a preferred vitamin C source for formulators who need reliable, long-shelf-life products for various industrial uses.

In skincare formulations, it functions as a brightening and antioxidant active in serums, creams, and toners, where conventional vitamin C would degrade before reaching the consumer. It is highly valued for its performance.

Pharmaceutical manufacturers use it as a stable vitamin C intermediate in oral supplements and nutraceutical blends targeting antioxidant support. It meets rigorous quality standards including USP and Ph.Eur. requirements.

Food and beverage producers incorporate it as a nutrient fortifier in functional products where ascorbic acid stability is a limiting factor. It is often produced to meet FCC and BP specifications for safety.

It also appears in topical pharmaceutical preparations requiring controlled vitamin C delivery without the formulation challenges associated with unstable ascorbate forms. This versatility is key for modern EP and ACS grade applications.

Ascorbyl glucoside is supplied as a white to off-white crystalline powder. Standard commercial concentrations include high-purity grades of 98% and above, with cosmetic-grade and food-grade specifications available for clients.

Bulk quantities are typically offered alongside smaller packaging options suited to R&D and pilot-scale formulation work. This ensures that manufacturers can scale their production from laboratory testing to full commercial distribution.

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Physical Properties

Melting Point158-163°C
Boiling Point785.6±60.0 °C(Predicted)
Density1.83±0.1 g/cm3(Predicted)
ColorWhite to Off-white
FormPowder
Water SolubilitySoluble in water. (879 g/L) at 25°C.
Vapor Pressure0Pa at 25℃
Log P-2 at 20℃

Trade & Regulatory

HS Code2938909090
Storage Class11 - Combustible Solids
WGK (Germany)3

Other Names

L-ascorbic acid 2-glucoside | AA-2G | 2-O-alpha-D-glucopyranosyl-L-ascorbic acid | 2V52R0NHXW | skin whitening | RefChem:58140 | GlyTouCan:G32886OM | L-Ascorbic acid2-O-α-D-glucopyranosyl-

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Chemical Properties

CAS Number
129499-78-1
EC Number
603-337-7
Mol. Weight
338.26
HS Code
2938909090

Industries

Documentation