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Vitamins & Nutrients

Ethyl ascorbic acid

CAS: 86404-04-8

Overview

Ethyl ascorbic acid ( CAS 86404-04-8 ), also known as 3-O-Ethyl Ascorbic Acid or VCE, is a stabilized ether derivative of Vitamin C used as a skin-brightening and antioxidant active in cosmetic formulations.

Unlike pure ascorbic acid, it maintains stability in aqueous systems while delivering bioavailable Vitamin C to skin tissue. It is a high-demand ingredient among formulators developing advanced skincare actives.

The primary application is in brightening serums and creams, where it targets uneven skin tone and hyperpigmentation in leave-on formulations. It is incorporated into anti-aging products alongside niacinamide or retinol.

These formulations deliver antioxidant protection and support collagen synthesis claims. Toners and ampoules in the K-beauty and prestige skincare segments frequently feature it as a lead active at specific concentrations.

Usage levels typically range from 1% to 3% depending on the desired efficacy. Sunscreen formulations also use it as an antioxidant booster to complement UV filter systems for enhanced skin protection.

Ethyl ascorbic acid is supplied as a white to off-white crystalline powder. It is available in cosmetic-grade specification, the standard for personal care applications, with purity typically at 98% or above.

Packaging is commonly offered in kilogram quantities up to bulk drum supply to serve both development-scale and commercial production needs. This ensures reliable supply chains for global manufacturers.

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Physical Properties

Melting Point116-117.5 °C
Boiling Point551.5±50.0 °C(Predicted)
Density1.46±0.1 g/cm3(Predicted)
ColorWhite to Off-White
FormSolid
Vapor Pressure0-0Pa at 20-25℃
Log P-0.8--0.64 at 20-25℃ and pH7

Safety & Handling

Warning GHS07 Hazard Statements H319 Causes serious eye irritation Precautionary Statements P280 Wear protective gloves/protective clothing/eye protection/face protection. P264+P265 Wash … thoroughly after handling. P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code2936.27.0000
Storage Class11 - Combustible Solids
WGK (Germany)3

Other Names

(2R)-2-[(1S)-12-dihydroxyethyl]-3-ethoxy-4-hydroxy-2H-furan-5-one | 3-o-ethyl ascorbic acid | VCE

Related Products

Chemical Properties

CAS Number
86404-04-8
EC Number
617-849-3
Mol. Weight
204.18
HS Code
2936.27.0000

Industries

Documentation