Salcaprozate sodium

Salcaprozate sodium (CAS 203787-91-1 ), also known by its E-number E414 , is a synthetic sodium salt used in pharmaceutical formulations as an absorption enhancer and carrier.

It improves the mucosal permeability of poorly absorbed active pharmaceutical ingredients, enabling effective oral or transmucosal drug delivery for various therapeutic applications.

Its primary use is in oral peptide and protein drug formulations, where it facilitates gastrointestinal absorption of biologics such as insulin and GLP-1 analogues.

It is also used for other macromolecules that would otherwise have negligible bioavailability. This compound is a critical excipient in approved and investigational oral tablet formulations.

These formulations target diabetes and other metabolic conditions. It is also evaluated in buccal and nasal delivery systems where enhanced mucosal uptake of peptide APIs is required.

Formulators working on next-generation oral biologics regularly specify this compound during early-phase development and scale-up to ensure consistent performance and delivery.

Salcaprozate sodium is supplied as a white to off-white powder. It is available in pharmaceutical-grade specifications suitable for GMP manufacturing environments with full documentation.

These packages support regulatory submissions for global markets. Quantities range from research-scale to commercial bulk, depending on the specific manufacturing capabilities required.

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