Overview
L-Theanine (CAS 3081-61-6 ), also known as N-Ethyl-L-glutamine, is a naturally occurring amino acid derived primarily from green tea. In commercial formulations, it functions as a bioactive ingredient valued for its calming and focus-supporting properties.
This versatile compound is utilized across the nutraceutical, pharmaceutical, and personal care markets. In dietary supplements, it is a primary active ingredient in stress-relief, sleep support, and cognitive performance products.
It is often combined with caffeine in capsule or tablet formats to enhance mental clarity. Food and beverage manufacturers incorporate it into functional drinks, nootropic shots, and fortified snacks targeting relaxation without sedation.
Pharmaceutical formulators use it as an excipient with mild buffering capacity and as an active in OTC wellness preparations. In personal care, it is used in moisturizing and antioxidant skincare formulations.
Its unique amino acid structure supports humectancy and skin-conditioning performance in topical applications. L-Theanine is supplied as a white crystalline powder for easy integration into various manufacturing processes.
Standard grades include food-grade and USP -compliant specifications, with purity levels typically at 98% or higher. These high standards ensure safety and efficacy for sensitive consumer applications.
Bulk quantities are available for industrial formulation, with smaller packaging options suited to nutraceutical compounding. This flexibility allows for both large-scale production and specialized laboratory use.
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Physical Properties
| Melting Point | 217-220 °C |
| Boiling Point | 430.2±40.0 °C(Predicted) |
| Density | 1.171±0.06 g/cm3(Predicted) |
| Appearance | White Crystalline Solid |
| Color | White |
| Odor | Odorless |
| Form | powder |
| Water Solubility | almost transparency |
| Refractive Index | 8 ° (C=5, H2O) |
| Log P | -0.661 (est) |
Safety & Handling
Warning GHS07 Hazard Statements H317 H317 Precautionary Statements P261 P261 P272 P272 P280 P280 P321 P321 P501 P501 P302+P352 P302+P352 P333+P317 P333+P317 P362+P364 P362+P364
Trade & Regulatory
| HS Code | 29241990 |
Other Names
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Chemical Properties
- CAS Number
- 3081-61-6
- EC Number
- 221-379-0
- Mol. Weight
- 174.20
- HS Code
- 29241990
- Category
- Amino Acids & Peptides