Overview
L-Glutamine (CAS 56-85-9 ), abbreviated Gln, is a conditionally essential amino acid produced commercially for use across pharmaceutical, nutritional, and cosmetic manufacturing.
It functions primarily as a nitrogen donor and metabolic substrate in biological systems, making it a core ingredient in products designed to support cellular nutrition.
FEMA 3684 status reflects its recognized role as a flavoring and nutrient component in food applications. In clinical nutrition, Gln is incorporated into parenteral solutions.
Sports nutrition manufacturers use it as an active ingredient in recovery powders and functional beverages. Food producers apply it as a flavor enhancer and fermentation nutrient.
In cosmetic and personal care products, it acts as a humectant and stabilizer in skin-conditioning formulations, contributing to moisture retention in various creams and serums.
L-Glutamine is supplied as a white crystalline powder in both food-grade and pharmaceutical-grade specifications. Recognized grades include USP , BP , Ph. Eur. , and FCC .
Pharmaceutical grades are subject to stricter purity and endotoxin controls. Bulk supply is standard in multi-kilogram bags through to metric ton quantities depending on application grade.
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Physical Properties
| Melting Point | 185.5 °C (decomp) |
| Boiling Point | 265.74°C (rough estimate) |
| Density | 1.00239 g/cm³ (Solid) @ Temp: 25 °C |
| Flash Point | 185°C |
| Appearance | White crystalline powder |
| Color | White |
| Odor | at 100.00 %. very mild milky custard cocoa oily |
| Form | solution |
| Water Solubility | Soluble in water, dimethyl sulfoxide and ethanol. Insoluble in methanol, ether, benzene, acetone, ethyl acetate and chloroform. |
| Refractive Index | 6.8 ° (C=4, H2O) |
| pH | 5.0-6.0 (25℃, 0.1M in H2O) |
| Log P | -1.67 |
Trade & Regulatory
| HS Code | 29241900 |
| Storage Class | 11 - Combustible Solids |
| WGK (Germany) | 2 |
Other Names
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Chemical Properties
- CAS Number
- 56-85-9
- EC Number
- 200-292-1
- Mol. Weight
- 146.14
- HS Code
- 29241900
- Category
- Vitamins & Nutrients