Dipicolinic acid

CAS: 499-83-2

Overview

Dipicolinic acid (CAS 499-83-2 ), commonly abbreviated as DPA, is a pyridine-based dicarboxylic acid used across food, cosmetic, and industrial chemistry applications. It functions primarily as a chelating agent, catalyst precursor, and preservation-active compound in formulated systems.

In food and flavoring applications, DPA acts as an acidulant and flavor modifier in processed formulations where precise pH control and taste profile adjustment are required. Its strong metal-chelating capacity makes it a valued precursor in catalyst preparation.

This material is particularly useful for coordination complexes used in organic synthesis and polymerization processes. In personal care and cosmetic formulations, DPA contributes to preservation systems by disrupting microbial activity.

By reducing reliance on conventional biocides, it offers a versatile solution for modern formulators. Industrial buyers also source it for use in analytical chemistry and as a reference standard for spore detection assays.

DPA is a recognized biomarker for bacterial endospores, making it essential for specialized laboratory testing. Dipicolinic acid is supplied as a white to off-white crystalline powder for various industrial needs.

It is available in technical grade for industrial and catalytic applications, as well as high-purity grades suited to analytical, food, and cosmetic end uses. Standard packaging ranges from laboratory-scale quantities to bulk orders.

Physical Properties

Melting Point	249 °C (decomp)
Boiling Point	295.67°C (rough estimate)
Density	1.5216 (rough estimate)
Flash Point	188 °C
Appearance	White crystalline powder
Color	White
Form	Crystalline Powder
Water Solubility	5 g/L (20 ºC)
Vapor Pressure	<0.01 hPa (20 °C)
Refractive Index	1.6280 (estimate)
pH	2.0 (5g/l, H2O, 20℃)
Log P	0.3 at 25℃ and pH1.8

Safety & Handling

Danger GHS05 GHS07 Hazard Statements H314 Causes severe skin burns and eye damage H315 Causes skin irritation H318 Causes serious eye damage H319 Causes serious eye irritation H335 May cause respiratory irritation Precautionary Statements P260 Do not breathe dust/fume/gas/mist/vapours/spray. P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P264 Wash … thoroughly after handling. P271 Use only outdoors or in a well-ventilated area. P280 Wear protective gloves/protective clothing/eye protection/face protection. P316 Get emergency medical help immediately. P317 Get emergency medical help. P319 Get medical advice/attention if you feel unwell. P321 Specific treatment (see … on this label). P363 Wash contaminated clothing before reuse. P405 Store locked up. P501 Dispose of contents/container in accordance with local regulations. P264+P265 Wash … thoroughly after handling. P302+P352 IF ON SKIN: Wash with plenty of water. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P332+P317 Get emergency medical help. P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P403+P233 Store in a well-ventilated place. Keep container tightly closed. P301+P330+P331 Rinse mouth. Do NOT induce vomiting. P302+P361+P354 IF ON SKIN: Take off immediately all contaminated clothing. Rinse skin with water/shower. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P305+P354+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code	29333999
WGK (Germany)	3

Other Names

Industries

Food & Nutrition Personal Care & Cosmetics