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Amino Acids & Peptides

D-alanine

CAS: 338-69-2

Overview

D-Alanine (CAS 338-69-2 ), also known as D-Ala, is the D-enantiomer of the naturally occurring amino acid alanine. It functions as a chiral building block, buffering agent, and stabilizer across pharmaceutical and cosmetic applications.

Demand is driven primarily by its role in synthesizing peptide-based active ingredients and pharmaceutical intermediates where enantiomeric purity is critical. In pharmaceutical manufacturing, it is used as a chiral intermediate.

It is essential in the synthesis of peptide antibiotics, enzyme inhibitors, and other stereospecific active compounds. Cosmetic formulators incorporate it into skin care products for its moisturizing and pH-buffering properties.

It is particularly effective in serums and treatment creams targeting hydration. In food and nutrition, it functions as a flavor modifier and stabilizer in specialty formulations, including amino acid-enriched dietary supplements.

Research and peptide synthesis laboratories also source it as a building block for custom peptide sequences requiring non-natural amino acid incorporation. This versatility makes it a staple in modern chemical synthesis.

The product is supplied as a white crystalline powder. It is available in pharmaceutical-grade ( USP / BP ) and reagent-grade specifications to meet the purity requirements of different industrial end markets.

Packaging ranges from small quantities for laboratory and R&D use to bulk quantities for industrial peptide synthesis. We ensure high-quality standards for commercial formulation and large-scale manufacturing needs.

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Physical Properties

Melting Point292 °C
Boiling Point212.9±23.0 °C(Predicted)
Density1.4310 (estimate)
AppearanceWhite Crystalline Powder
ColorWhite to off-white
Odorodorless
FormCrystalline Powder or Crystals
Water Solubility155 g/L (20 ºC)
Refractive Index-14 ° (C=2, 6mol/L HCl)
Log P-0.574 (est)

Safety & Handling

Warning GHS07 Hazard Statements H315 Causes skin irritation H319 Causes serious eye irritation H335 May cause respiratory irritation Precautionary Statements P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P264 Wash … thoroughly after handling. P271 Use only outdoors or in a well-ventilated area. P280 Wear protective gloves/protective clothing/eye protection/face protection. P319 Get medical advice/attention if you feel unwell. P321 Specific treatment (see … on this label). P405 Store locked up. P501 Dispose of contents/container in accordance with local regulations. P264+P265 Wash … thoroughly after handling. P302+P352 IF ON SKIN: Wash with plenty of water. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P332+P317 Get emergency medical help. P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P403+P233 Store in a well-ventilated place. Keep container tightly closed. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29224900
Storage Class11 - Combustible Solids
WGK (Germany)3

Other Names

(2R)-2-aminopropanoic acid | D-2-Aminopropionic acid | D-Ala | D-alpha-Alanine | AlanineD- | Alanine D-form | (R)-2-Aminopropionic acid | Ba 2776

Related Products

Chemical Properties

CAS Number
338-69-2
EC Number
206-418-1
Mol. Weight
89.09
HS Code
29224900

Industries

Documentation