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Chelating Agents

Calcium lactobionate

CAS: 5001-51-4

Overview

Calcium lactobionate (CAS 5001-51-4 ), also identified by E-number E399 , is the calcium salt of lactobionic acid used across food, cosmetic, and pharmaceutical manufacturing.

It functions primarily as a chelating agent, humectant, and stabilizer, helping formulators manage mineral interactions, moisture retention, and oxidative stability in finished products.

In food and beverage manufacturing, it acts as a firming agent and sequestrant, protecting product texture and color by binding trace metals that would otherwise accelerate spoilage.

Pharmaceutical manufacturers use it as a calcium supplement source and as a stabilizing excipient in oral and parenteral formulations where controlled mineral delivery is required.

In cosmetic and skincare formulations, its moisture-binding capacity supports hydration claims in serums, creams, and leave-on treatments for various skin types.

It also serves as a processing aid in dairy applications, where calcium fortification and texture stabilization are required simultaneously to maintain high product quality.

Calcium lactobionate is supplied as a white crystalline powder, available in both anhydrous and monohydrate forms. Standard grades include food-grade and pharmaceutical-grade material.

Our inventory meets USP or Ph. Eur. specifications. Packaging is typically offered in multi-kilogram bags or drums suited to industrial procurement volumes.

Contact us for supply of Calcium lactobionate

Physical Properties

Melting Point~190 °C (dec.)
AppearanceWhite powder. Sol in water; insol in alc, ether.
ColorWhite to Almost white
Formpowder to crystal
Refractive Index24 ° (C=6, H2O)
Log P-4.058 (est)

Safety & Handling

Warning GHS07 Hazard Statements H302 Harmful if swallowed H312 Harmful in contact with skin H315 Causes skin irritation H319 Causes serious eye irritation H332 Harmful if inhaled H335 May cause respiratory irritation Precautionary Statements P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P264 Wash … thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P271 Use only outdoors or in a well-ventilated area. P280 Wear protective gloves/protective clothing/eye protection/face protection. P317 Get emergency medical help. P319 Get medical advice/attention if you feel unwell. P321 Specific treatment (see … on this label). P330 Rinse mouth. P405 Store locked up. P501 Dispose of contents/container in accordance with local regulations. P264+P265 Wash … thoroughly after handling. P301+P317 Get emergency medical help. P302+P352 IF ON SKIN: Wash with plenty of water. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P332+P317 Get emergency medical help. P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P403+P233 Store in a well-ventilated place. Keep container tightly closed. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code2940.00.6000
WGK (Germany)3

Other Names

calcium lactobionate anhydrous | Lactobionic acidcalcium salt (2:1) | 258F856K63 | Calcium bis(4-O-(beta-D-galactosyl)-D-gluconate) | D-Gluconic acid4-O-beta-D-galactopyranosyl-calcium salt (2:1) | RefChem:200044 | Lactobionic acid calcium salt | E399

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Chemical Properties

CAS Number
5001-51-4
EC Number
225-668-2
Mol. Weight
754.7
HS Code
2940.00.6000

Industries

Documentation