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Amines

Methyl diisopropyl propionamide

CAS: 51115-67-4

Overview

Methyl diisopropyl propionamide (CAS 51115-67-4 ), widely recognized in the flavor and personal care industries as WS-23 , is a synthetic cooling agent that delivers a clean sensation.

It provides a non-menthol cooling effect without the associated taste or odor. Registered under FEMA 3804 , it is used across food, beverage, oral care, and cosmetic applications.

In flavored products including chewing gum, mints, and confectionery, it provides intense cooling at low use levels. This allows formulators to reduce or replace menthol entirely in their recipes.

Oral care manufacturers incorporate it into toothpastes, mouthwashes, and breath strips. It is preferred where a clean cooling effect is desired over a traditional mint flavor profile.

In personal care, it is used in lip balms, skin gels, and after-sun products. It delivers a sensory cooling effect that enhances the consumer perception of freshness and relief.

Home care formulators also use it in surface sprays and fabric conditioners. It adds a cooling freshness cue to the product experience, improving the overall brand perception for users.

The product is supplied as a white crystalline powder or in liquid carrier solutions. It is available in food-grade quality conforming to FEMA specifications for various industries.

Technical grades are also offered for non-ingestible applications. Typical supply formats include bulk powder and pre-diluted concentrates for ease of handling in manufacturing facilities.

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Physical Properties

Melting Point60 °C
Boiling Point84 °C
Density0.9419 (rough estimate)
ColorWhite to Almost white
Odorat 25.00 % in dipropylene glycol. mild cooling mentholic minty
FormSolid
Vapor Pressure0.3-0.32Pa at 25℃
Refractive Index1.4621 (estimate)
Log P2.5 at 25℃ and pH7

Safety & Handling

Warning GHS07 Hazard Statements H302 Harmful if swallowed Precautionary Statements P264 Wash … thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P330 Rinse mouth. P501 Dispose of contents/container in accordance with local regulations. P301+P317 Get emergency medical help.

Trade & Regulatory

HS Code29242990
Storage Class11 - Combustible Solids
WGK (Germany)3

Other Names

2-Isopropyl-N23-trimethylbutanamide | 2-Isopropyl-N23-trimethylbutyramide | N23-trimethyl-2-propan-2-ylbutanamide | WS-23 | N23-Trimethyl-2-(1-methylethyl)butanamide | Trimethyl isopropyl butanamide | N23-Trimethyl-2-isopropylbutanamide | ButanamideN23-trimethyl-2-(1-methylethyl)-

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Chemical Properties

CAS Number
51115-67-4
EC Number
256-974-4
Mol. Weight
171.28
HS Code
29242990
Category
Amines

Industries

Documentation