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Heterocyclic Compounds

Matrine

CAS: 519-02-8

Overview

Matrine (CAS 519-02-8 ) is a naturally derived alkaloid extracted from Sophora root, recognized in agricultural and pharmaceutical sourcing under the designation NSC-146051.

It functions as a bioactive agent with preservation, stabilization, and UV-protective properties across multiple formulated product categories. In agricultural formulations, it is used as a botanical biopesticide.

It is incorporated into crop protection products where synthetic chemical restrictions apply or where organic certification is required. Personal care formulators incorporate it into UV-protective and antioxidant products.

This is particularly common in markets where plant-derived actives are preferred over synthetic stabilizers. In pharmaceutical and nutraceutical development, it serves as a reference compound and active ingredient.

It is a candidate in finished dosage form research. Agricultural feed applications also utilize matrine-based preparations as a natural preservative component to extend product stability and shelf life.

The product is supplied as a white to off-white crystalline powder. It is available in varying purity grades, with high-purity specifications commonly used in pharmaceutical and research applications.

Lower-purity technical grades serve agricultural and industrial formulation needs. Packaging options typically range from small research quantities to bulk kilogram-scale orders depending on requirements.

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Physical Properties

Melting Point76 °C
Boiling Point223 °C @ Press: 6 Torr
Density1.0888 g/cm³ @ Temp: 85 °C
ColorWhite
Formsolid
Refractive Index1,536
Log P1.440 (est)

Safety & Handling

Warning GHS07 Hazard Statements H302 Harmful if swallowed H319 Causes serious eye irritation Precautionary Statements P264 Wash … thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P280 Wear protective gloves/protective clothing/eye protection/face protection. P330 Rinse mouth. P501 Dispose of contents/container in accordance with local regulations. P264+P265 Wash … thoroughly after handling. P301+P317 Get emergency medical help. P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29399900
Storage Class11 - Combustible Solids
WGK (Germany)3

Other Names

Vegard | N390W430AC | (1R2R9S17S)-713-diazatetracyclo[7.7.1.027.01317]heptadecan-6-one | Matridin-15-one | BITTER SOPHORA ROOT EXTRACT

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Chemical Properties

CAS Number
519-02-8
EC Number
610-750-6
Mol. Weight
248.36
HS Code
29399900

Industries

Documentation