Overview
Matrine (CAS 519-02-8 ) is a naturally derived alkaloid extracted from Sophora root, recognized in agricultural and pharmaceutical sourcing under the designation NSC-146051.
It functions as a bioactive agent with preservation, stabilization, and UV-protective properties across multiple formulated product categories. In agricultural formulations, it is used as a botanical biopesticide.
It is incorporated into crop protection products where synthetic chemical restrictions apply or where organic certification is required. Personal care formulators incorporate it into UV-protective and antioxidant products.
This is particularly common in markets where plant-derived actives are preferred over synthetic stabilizers. In pharmaceutical and nutraceutical development, it serves as a reference compound and active ingredient.
It is a candidate in finished dosage form research. Agricultural feed applications also utilize matrine-based preparations as a natural preservative component to extend product stability and shelf life.
The product is supplied as a white to off-white crystalline powder. It is available in varying purity grades, with high-purity specifications commonly used in pharmaceutical and research applications.
Lower-purity technical grades serve agricultural and industrial formulation needs. Packaging options typically range from small research quantities to bulk kilogram-scale orders depending on requirements.
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Physical Properties
| Melting Point | 76 °C |
| Boiling Point | 223 °C @ Press: 6 Torr |
| Density | 1.0888 g/cm³ @ Temp: 85 °C |
| Color | White |
| Form | solid |
| Refractive Index | 1,536 |
| Log P | 1.440 (est) |
Safety & Handling
Warning GHS07 Hazard Statements H302 Harmful if swallowed H319 Causes serious eye irritation Precautionary Statements P264 Wash … thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P280 Wear protective gloves/protective clothing/eye protection/face protection. P330 Rinse mouth. P501 Dispose of contents/container in accordance with local regulations. P264+P265 Wash … thoroughly after handling. P301+P317 Get emergency medical help. P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Trade & Regulatory
| HS Code | 29399900 |
| Storage Class | 11 - Combustible Solids |
| WGK (Germany) | 3 |
Other Names
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Chemical Properties
- CAS Number
- 519-02-8
- EC Number
- 610-750-6
- Mol. Weight
- 248.36
- HS Code
- 29399900
- Category
- Heterocyclic Compounds