Overview
N,N-bis(2-hydroxyethyl)-p-phenylenediamine sulfate (CAS 54381-16-7 ) is an oxidative hair dye intermediate used to develop color in permanent and semi-permanent hair coloring systems.
Supplied as a stable sulfate salt, it functions as a primary coupler or developer component that reacts with oxidizing agents to produce targeted color shades for various applications.
In professional and retail hair color formulations, it is combined with hydrogen peroxide and coupling agents to achieve brown, auburn, and neutral tone results across different hair types.
Textile dyeing operations use it as a dye intermediate for producing azo and oxidation dyes on natural and synthetic fiber substrates. It ensures consistent color depth and durability.
In leather finishing, it contributes to surface coloration processes where controlled oxidative dyeing is required. Paper manufacturers incorporate it in specialty coloring applications for uniform pigmentation.
The product is supplied as a crystalline powder or fine solid. It is available in cosmetic-grade specifications aligned with requirements for use in regulated personal care formulations.
This includes compliance with EU Cosmetics Regulation annex listings. Technical-grade material is also available for textile and industrial dyeing applications requiring high purity and stability.
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Physical Properties
| Melting Point | 168-171°C |
| Boiling Point | 125°C[at 101 325 Pa] |
| Density | 1.497[at 20℃] |
| Appearance | White crystal powder |
| Color | White to Off-White |
| Form | Solid |
| Water Solubility | 178g/L at 20℃ |
| Vapor Pressure | 65Pa at 20℃ |
| Log P | -2.8 at 20℃ |
Safety & Handling
Danger GHS06 GHS07 GHS09 Hazard Statements H301 Toxic if swallowed H311 Toxic in contact with skin H315 Causes skin irritation H317 May cause an allergic skin reaction H319 Causes serious eye irritation H331 Toxic if inhaled H400 Very toxic to aquatic life H410 Very toxic to aquatic life with long lasting effects H411 Toxic to aquatic life with long lasting effects Precautionary Statements P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P262 Do not get in eyes, on skin, or on clothing. P264 Wash … thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P271 Use only outdoors or in a well-ventilated area. P272 Contaminated work clothing should not be allowed out of the workplace. P273 Avoid release to the environment. P280 Wear protective gloves/protective clothing/eye protection/face protection. P316 Get emergency medical help immediately. P321 Specific treatment (see … on this label). P330 Rinse mouth. P391 Collect spillage. P405 Store locked up. P501 Dispose of contents/container in accordance with local regulations. P264+P265 Wash … thoroughly after handling. P301+P316 Get emergency medical help immediately. P302+P352 IF ON SKIN: Wash with plenty of water. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P332+P317 Get emergency medical help. P333+P317 Get emergency medical help. P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help. P361+P364 Take off immediately all contaminated clothing and wash it before reuse. P362+P364 Take off contaminated clothing and wash it before reuse. P403+P233 Store in a well-ventilated place. Keep container tightly closed. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Trade & Regulatory
| HS Code | 29309090 |
| Storage Class | 11 - Combustible Solids |
| WGK (Germany) | 3 |
Other Names
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Chemical Properties
- CAS Number
- 54381-16-7
- EC Number
- 259-134-5
- Mol. Weight
- 294.33
- HS Code
- 29309090
- Category
- Pigments & Colorants