Overview
Menadione (CAS 58-27-5 ), commonly known as Vitamin K3, is a synthetic naphthalene-based compound used as a precursor and active ingredient across pharmaceutical and industrial manufacturing.
It functions as an antioxidant stabilizer and catalytic intermediate in formulations where controlled oxidation activity is required. In pharmaceutical manufacturing, it serves as a starting material for producing Vitamin K analogues.
These analogues are used in injectable and oral dosage forms. Cosmetic formulators incorporate it into antioxidant-active preparations targeting skin conditioning and stability enhancement in various topical applications.
In textile and paper processing, it functions as a catalytic agent in dye fixation and oxidative finishing processes. Leather treatment operations also utilize it as a processing aid where controlled redox activity supports outcomes.
Menadione is supplied as a yellow crystalline powder, which is the standard physical form across commercial grades. Pharmaceutical-grade material is available to USP and BP specifications for regulated environments.
Technical-grade product is offered for industrial applications in textile, paper, and leather processing where compendial certification is not required. This ensures versatility across multiple manufacturing sectors and chemical processes.
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Physical Properties
| Melting Point | 105-107 °C |
| Boiling Point | 314 °C |
| Density | 1.1153 (rough estimate) |
| Appearance | Bright yellow crystals |
| Color | yellow |
| Odor | Slight odor |
| Form | crystalline |
| Water Solubility | INSOLUBLE |
| Refractive Index | 1.5500 (estimate) |
| Log P | 2.200 |
Safety & Handling
Warning GHS07 GHS09 Hazard Statements H302 H302 H315 H315 H317 H317 H319 H319 H335 H335 H400 H400 H410 H410 Precautionary Statements P261 P261 P264 P264 P270 P270 P271 P271 P272 P272 P273 P273 P280 P280 P319 P319 P321 P321 P330 P330 P391 P391 P405 P405 P501 P501 P264+P265 P264+P265 P301+P317 P301+P317 P302+P352 P302+P352 P304+P340 P304+P340 P332+P317 P332+P317 P333+P317 P333+P317 P337+P317 P337+P317 P362+P364 P362+P364 P403+P233 P403+P233 P305+P351+P338 P305+P351+P338
Trade & Regulatory
| HS Code | 29146900 |
| Storage Class | 11 - Combustible Solids |
| WGK (Germany) | 3 |
Other Names
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Chemical Properties
- CAS Number
- 58-27-5
- EC Number
- 200-372-6
- Mol. Weight
- 172.18
- HS Code
- 29146900
- Category
- Heterocyclic Compounds