Overview
p-Toluenesulfonic acid monohydrate (CAS 6192-52-5 ), commonly abbreviated as PTSA, is a strong organic acid supplied in stable, water-containing crystalline form.
It functions primarily as an acid catalyst and pH-regulating agent across a broad range of industrial synthesis and formulation processes for various chemical applications.
In coatings and adhesives, PTSA acts as a curing catalyst for amino and epoxy resin systems, accelerating crosslinking to improve hardness and chemical resistance in finished films.
Polymer manufacturers use it to catalyze esterification, condensation, and polymerization reactions where precise acid strength and handling stability are critical for production.
In pharmaceutical synthesis, PTSA serves as a salt-forming agent to improve the stability and bioavailability of active ingredients, as tosylate salts are a recognized form.
Textile processors apply it for pH control and surface modification during dyeing and finishing operations to ensure consistent quality and performance in the final fabric products.
The product is supplied as a white to off-white crystalline solid. Standard commercial grades include technical and pharmaceutical-grade material conforming to USP and Ph. Eur. specifications.
It is typically packaged in moisture-resistant containers to preserve stability during storage and transit, ensuring the material remains effective for its intended industrial use.
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Physical Properties
| Melting Point | 103-106 °C |
| Boiling Point | 92-119 °C |
| Density | 1,24 g/cm 3 |
| Flash Point | 180 °C |
| Appearance | White crystals |
| Color | White to pink |
| Form | Solid |
| Water Solubility | soluble |
| Refractive Index | 1,382-1,384 |
| pH | 1 (650g/l, H2O, 20℃)(anhydrous substance) |
Safety & Handling
Danger GHS05 GHS07 Hazard Statements H302 Harmful if swallowed H314 Causes severe skin burns and eye damage H315 Causes skin irritation H318 Causes serious eye damage H319 Causes serious eye irritation H335 May cause respiratory irritation Precautionary Statements P260 Do not breathe dust/fume/gas/mist/vapours/spray. P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P264 Wash … thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P271 Use only outdoors or in a well-ventilated area. P280 Wear protective gloves/protective clothing/eye protection/face protection. P316 Get emergency medical help immediately. P317 Get emergency medical help. P319 Get medical advice/attention if you feel unwell. P321 Specific treatment (see … on this label). P330 Rinse mouth. P363 Wash contaminated clothing before reuse. P405 Store locked up. P501 Dispose of contents/container in accordance with local regulations. P264+P265 Wash … thoroughly after handling. P301+P317 Get emergency medical help. P302+P352 IF ON SKIN: Wash with plenty of water. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P332+P317 Get emergency medical help. P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P403+P233 Store in a well-ventilated place. Keep container tightly closed. P301+P330+P331 Rinse mouth. Do NOT induce vomiting. P302+P361+P354 IF ON SKIN: Take off immediately all contaminated clothing. Rinse skin with water/shower. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P305+P354+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Trade & Regulatory
| HS Code | 29041000 |
| UN Number | 2585 |
| ADR Class | 8 |
| Packing Group | III |
| Storage Class | 8A - Combustible corrosive hazardous materials |
Other Names
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Chemical Properties
- CAS Number
- 6192-52-5
- EC Number
- 612-715-0
- Mol. Weight
- 190.22
- HS Code
- 29041000
- Category
- Surfactants