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Pharmaceutical Intermediates

p-coumaric acid

CAS: 7400-08-0

Overview

p-Coumaric acid (CAS 7400-08-0 ), also recognized commercially as p-hydroxycinnamic acid, is a naturally occurring hydroxycinnamic acid sourced from plant extracts or produced synthetically for industrial supply.

It functions primarily as an antioxidant, UV-absorbing agent, and bioactive intermediate across pharmaceutical, nutraceutical, and cosmetic manufacturing. In pharmaceutical synthesis, it serves as a key intermediate.

This material is used in the production of active compounds, including resveratrol analogs and other polyphenolic APIs. Nutraceutical and functional food formulators incorporate it as a plant-derived antioxidant.

It is frequently found in dietary supplements, botanical extracts, and standardized herbal preparations. In cosmetic formulations, its UV-absorbing and antioxidant properties make it relevant for inclusion.

Common applications include sunscreen actives, anti-aging serums, and skin-brightening products. Food manufacturers also evaluate it as a natural antioxidant stabilizer in specialty food and beverage applications.

The product is supplied as an off-white to pale yellow crystalline powder. It is available in technical grade for industrial synthesis and in higher-purity grades for specialized manufacturing.

These include USP -aligned and research-grade specifications for pharmaceutical and nutraceutical applications. Packaging typically ranges from small quantities for development to bulk quantities.

Our supply chain ensures consistent quality for commercial-scale production. We provide comprehensive documentation to support regulatory compliance and formulation stability across all industrial sectors.

Contact us for supply of p-coumaric acid

Physical Properties

Melting Point211.5 °C
Boiling Point251.61°C (rough estimate)
Density1.2132 (rough estimate)
AppearanceLight yellow to beige crystalline powder
ColorWhite to Off-White
FormSolid
Refractive Index1.5380 (estimate)
Log P1.790

Safety & Handling

Warning GHS07 GHS05 GHS06 Hazard Statements H301 Toxic if swallowed H311 Toxic in contact with skin H314 Causes severe skin burns and eye damage H315 Causes skin irritation H317 May cause an allergic skin reaction H318 Causes serious eye damage H319 Causes serious eye irritation H335 May cause respiratory irritation H301+H311 Toxic if swallowed or in contact with skin Precautionary Statements P260 Do not breathe dust/fume/gas/mist/vapours/spray. P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P262 Do not get in eyes, on skin, or on clothing. P264 Wash … thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P271 Use only outdoors or in a well-ventilated area. P272 Contaminated work clothing should not be allowed out of the workplace. P280 Wear protective gloves/protective clothing/eye protection/face protection. P316 Get emergency medical help immediately. P317 Get emergency medical help. P319 Get medical advice/attention if you feel unwell. P321 Specific treatment (see … on this label). P330 Rinse mouth. P363 Wash contaminated clothing before reuse. P405 Store locked up. P501 Dispose of contents/container in accordance with local regulations. P264+P265 Wash … thoroughly after handling. P301+P316 Get emergency medical help immediately. P302+P352 IF ON SKIN: Wash with plenty of water. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P332+P317 Get emergency medical help. P333+P317 Get emergency medical help. P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help. P361+P364 Take off immediately all contaminated clothing and wash it before reuse. P362+P364 Take off contaminated clothing and wash it before reuse. P403+P233 Store in a well-ventilated place. Keep container tightly closed. P301+P330+P331 Rinse mouth. Do NOT induce vomiting. P302+P361+P354 IF ON SKIN: Take off immediately all contaminated clothing. Rinse skin with water/shower. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P305+P354+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code2918 29 00
Storage Class11 - Combustible Solids
WGK (Germany)2

Other Names

p-hydroxyphenylacrylic acid | p-hydroxycinnamic acid | beta-[4-hydroxyphenyl]acrylic acid | 4'-hydroxycinnamic acid | 3-(4-hydroxyphenyl)acrylic acid | 3-(4-hydroxyphenyl)-2-propenoic acid | para-coumaric acid | trans-p-Coumaric acid

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Chemical Properties

CAS Number
7400-08-0
EC Number
231-000-0
Mol. Weight
164.16
HS Code
2918 29 00

Industries

Documentation