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Heterocyclic Compounds

4-hydroxy acetophenone

CAS: 99-93-4

Overview

4-Hydroxyacetophenone (CAS 99-93-4 ), also known commercially as piceol, is a phenolic ketone used across food, cosmetic, and industrial manufacturing. It functions as a photoinitiator, antioxidant, and flavoring agent depending on the application sector.

In UV-curable systems for printing inks and packaging coatings, it acts as a photoinitiator to trigger polymerization under UV exposure. Cosmetic formulators incorporate it as an antioxidant and skin-brightening active in serums and creams.

In food and beverage, it is approved under FEMA 4330 as a flavoring ingredient, contributing subtle phenolic and sweet notes to finished products. It is also used as an intermediate in the synthesis of active pharmaceutical ingredients.

Pharmaceutical manufacturers source it particularly where a para-substituted acetophenone scaffold is required. The material is supplied as a white to off-white crystalline powder available in various technical and high-purity grades.

Our product meets rigorous quality standards including FCC , USP , Ph.Eur. , BP , EP , and ACS specifications. These grades are suited to pharmaceutical and food-grade requirements for global distribution.

Standard packaging options include fiber drums and multi-layer bags, with bulk quantities available for industrial procurement. We ensure consistent quality and reliable supply chains for all manufacturing sectors.

Contact us for supply of 4-hydroxy acetophenone

Physical Properties

Melting Point109.5 °C
Boiling Point146-149 °C
Density1.278 g/cm³ @ Temp: 25 °C
Flash Point166 °C
Appearancealmost white to beige crystalline powder
ColorAlmost white to beige
Odorat 10.00 % in dipropylene glycol. mild sweet hawthorn balsam mimosa
FormCrystalline Powder
Water Solubility10 g/L (22 ºC)
Vapor Pressure0.002Pa at 20℃
Refractive Index1.5577 (estimate)
Log P1.35 at 25℃

Safety & Handling

Warning GHS07 Hazard Statements H302 Harmful if swallowed H315 Causes skin irritation H319 Causes serious eye irritation H335 May cause respiratory irritation H412 Harmful to aquatic life with long lasting effects Precautionary Statements P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P264 Wash … thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P271 Use only outdoors or in a well-ventilated area. P273 Avoid release to the environment. P280 Wear protective gloves/protective clothing/eye protection/face protection. P319 Get medical advice/attention if you feel unwell. P321 Specific treatment (see … on this label). P330 Rinse mouth. P405 Store locked up. P501 Dispose of contents/container in accordance with local regulations. P264+P265 Wash … thoroughly after handling. P301+P317 Get emergency medical help. P302+P352 IF ON SKIN: Wash with plenty of water. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P332+P317 Get emergency medical help. P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P403+P233 Store in a well-ventilated place. Keep container tightly closed. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29145000
Storage Class13 - Non Combustible Solids
WGK (Germany)3

Other Names

piceol | para-Hydroxyacetophenone | p-Hydroxyphenyl methyl ketone | p-Hydroxyacetophenone | Methyl p-hydroxyphenyl ketone | 4-Acetylphenol | 1-(4-hydroxyphenyl)ethanone | (4-hydroxyphenyl)ethan-1-one

Related Products

Chemical Properties

CAS Number
99-93-4
EC Number
202-802-8
Mol. Weight
136.15
HS Code
29145000

Industries

Documentation