Sodium periodate

CAS: 7790-28-5

Overview

Sodium periodate (CAS 7790-28-5 ), also known as sodium metaperiodate, is a strong inorganic oxidizing agent used across industrial and laboratory-scale processes. It selectively cleaves diol bonds in carbohydrates and glycols.

This chemical serves as a standard reagent in pharmaceutical synthesis and analytical chemistry. In industrial settings, it functions as a bleaching and biocidal agent in water treatment, textile processing, and paper manufacturing.

In pharmaceutical and biochemical manufacturing, it is used to oxidize polysaccharides and glycoproteins. This is a critical step in conjugate vaccine production and drug intermediate synthesis for various medical applications.

Textile processors apply it to modify cellulose fibers, improving dye uptake and enabling functional finishing treatments. In water treatment, it acts as a biocide and oxidant to control microbial growth.

It is also used to break down organic contaminants in industrial effluent systems. Paper and pulp operations use it as a selective bleaching agent to improve brightness without degrading the underlying fiber structure.

The product is supplied as a white crystalline powder or granular solid. It is available in technical grade for industrial applications and in high-purity grades meeting reagent or ACS specifications.

These high-purity grades are ideal for pharmaceutical and analytical use. Packaging ranges from small laboratory quantities to bulk industrial supply, with moisture-controlled packaging standard for oxidizer-grade material.

Physical Properties

Melting Point	300 °C (dec.) (lit.)
Boiling Point	300°C
Density	3.86 g/cm³ (solid)
Appearance	white powder
Color	White to almost white
Odor	Odorless
Form	Solid
Water Solubility	80 g/L (20 ºC)
Vapor Pressure	0Pa at 20℃
pH	3.5-5.5 (25℃, 0.5M in H2O)
Log P	-1 at 20℃

Safety & Handling

Danger GHS03 GHS05 GHS06 GHS07 GHS08 GHS09 Hazard Statements H271 May cause fire or explosion; strong Oxidizer H272 May intensify fire; oxidizer H301 Toxic if swallowed H302 Harmful if swallowed H314 Causes severe skin burns and eye damage H315 Causes skin irritation H318 Causes serious eye damage H319 Causes serious eye irritation H335 May cause respiratory irritation H371 May cause damage to organs H372 Causes damage to organs through prolonged or repeated exposure H400 Very toxic to aquatic life Precautionary Statements P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking. P220 Keep away from clothing and other combustible materials. P260 Do not breathe dust/fume/gas/mist/vapours/spray. P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P264 Wash … thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P271 Use only outdoors or in a well-ventilated area. P273 Avoid release to the environment. P280 Wear protective gloves/protective clothing/eye protection/face protection. P283 Wear fire-resistant/flame-retardant clothing. P316 Get emergency medical help immediately. P317 Get emergency medical help. P319 Get medical advice/attention if you feel unwell. P321 Specific treatment (see … on this label). P330 Rinse mouth. P363 Wash contaminated clothing before reuse. P391 Collect spillage. P405 Store locked up. P420 Store away from other materials. P501 Dispose of contents/container in accordance with local regulations. P264+P265 Wash … thoroughly after handling. P301+P316 Get emergency medical help immediately. P301+P317 Get emergency medical help. P302+P352 IF ON SKIN: Wash with plenty of water. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P306+P360 IF ON CLOTHING: Rinse immediately contaminated clothing and skin with plenty of water before removing clothes. P308+P316 Get emergency medical help immediately. P332+P317 Get emergency medical help. P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P370+P378 Use … for extinction. P403+P233 Store in a well-ventilated place. Keep container tightly closed. P301+P330+P331 Rinse mouth. Do NOT induce vomiting. P302+P361+P354 IF ON SKIN: Take off immediately all contaminated clothing. Rinse skin with water/shower. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P305+P354+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P371+P380+P375 Evacuate area.

Trade & Regulatory

HS Code	28299080
UN Number	3087
ADR Class	5.1
Packing Group	II
Storage Class	5.1A - Strongly oxidizing hazardous materials
WGK (Germany)	3

Other Names

Industries

Water Treatment Pharmaceuticals & Healthcare Textile, Leather & Paper