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Heterocyclic Compounds

2-Phenylimidazoline

CAS: 936-49-2

Overview

2-Phenylimidazoline (CAS 936-49-2 ) is a cyclic amidine compound used primarily as a catalyst and pharmaceutical intermediate in fine chemical synthesis. It functions as a curing agent accelerator and reaction catalyst in specialized organic chemistry workflows.

In pharmaceutical manufacturing, this compound serves as a key building block for synthesizing active pharmaceutical ingredients and bioactive heterocyclic scaffolds. It acts as a catalyst in epoxy resin curing systems where controlled reactivity is a priority.

Low dosage requirements make it ideal for formulators working with complex resin systems. Biotechnology researchers use it as a synthetic intermediate in the preparation of imidazoline-class compounds studied for receptor binding activity.

It also appears in the production of specialty agrochemicals and fine chemicals where imidazoline ring systems are required structural components. This versatility makes it a staple in modern industrial chemical synthesis and development.

The product is typically supplied as a white to off-white crystalline solid. Standard commercial offerings include technical-grade and high-purity grades with a minimum assay of 98% or higher for sensitive applications.

Pharmaceutical-grade material is available from select manufacturers meeting USP or BP aligned specifications. Packaging ranges from small research quantities to multi-kilogram industrial lots depending on the specific supplier capability.

Quality control ensures that the material meets rigorous standards for moisture content and purity. This ensures consistent performance in both large-scale manufacturing and precision laboratory research environments across the globe.

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Physical Properties

Melting Point98-100 °C
Boiling Point162 °C
Density1,15 g/cm 3
Flash Point201 °C
AppearanceLIGHT YELLOW TO YELLOW FLAKES OR CRYST. POWDER
ColorPale brown
OdorFaint odor
FormPowder
Water SolubilitySOLUBLE
Vapor Pressure0.001Pa at 20℃
Refractive Index1.5600 (estimate)
Log P2.45 at 25℃

Safety & Handling

Danger GHS05 GHS07 GHS09 Hazard Statements H302 Harmful if swallowed H315 Causes skin irritation H318 Causes serious eye damage H319 Causes serious eye irritation H400 Very toxic to aquatic life H410 Very toxic to aquatic life with long lasting effects H411 Toxic to aquatic life with long lasting effects Precautionary Statements P264 Wash … thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P273 Avoid release to the environment. P280 Wear protective gloves/protective clothing/eye protection/face protection. P317 Get emergency medical help. P321 Specific treatment (see … on this label). P330 Rinse mouth. P391 Collect spillage. P501 Dispose of contents/container in accordance with local regulations. P264+P265 Wash … thoroughly after handling. P301+P317 Get emergency medical help. P302+P352 IF ON SKIN: Wash with plenty of water. P332+P317 Get emergency medical help. P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P305+P354+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29332900
UN Number3263
ADR Class8
Packing GroupII
Storage Class11 - Combustible Solids
WGK (Germany)3

Other Names

2-Phenyl-2-imidazoline | 1H-Imidazole45-dihydro-2-phenyl- | E78R99DCH8 | RefChem:478045 | 2-Imidazoline2-phenyl- | 45-Dihydro-2-phenyl-1H-imidazole

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Chemical Properties

CAS Number
936-49-2
EC Number
213-313-4
Mol. Weight
146.19
HS Code
29332900

Industries

Documentation