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Heterocyclic Compounds

Lansoprazole

CAS: 103577-45-3

Overview

Lansoprazole (CAS 103577-45-3 ), also referenced under development codes AG-1749 and A-65006, and widely recognized by the brand name Prevacid, is a proton pump inhibitor (PPI) active pharmaceutical ingredient.

It is used in the treatment of acid-related gastrointestinal disorders and functions by irreversibly blocking gastric acid secretion, making it a core API in prescription and over-the-counter drug formulations globally.

Lansoprazole is formulated into delayed-release capsules and orally disintegrating tablets targeting conditions such as gastroesophageal reflux disease (GERD), peptic ulcer disease, and Zollinger-Ellison syndrome.

It is also incorporated into combination therapy regimens for Helicobacter pylori eradication, typically alongside antibiotics and bismuth compounds for effective clinical outcomes in patients.

Generic pharmaceutical manufacturers source it as a bulk API for solid dosage form production across regulated and semi-regulated markets. Contract development and manufacturing organizations utilize it in novel delivery formats.

These formats include enteric-coated pellet systems designed to protect the compound from gastric degradation. Lansoprazole is supplied as a white to off-white crystalline powder in bulk quantities for manufacturing.

It is available in USP , BP , and Ph. Eur. pharmacopoeial grades to meet the regulatory requirements of major markets including the US, EU, and UK. This ensures high quality for global distribution.

Packaging is typically offered in double-polyethylene-lined fiber drums under controlled storage conditions. This ensures the stability and integrity of the pharmaceutical ingredient during long-term transit.

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Physical Properties

Melting Point178-182 °C (decomp)
Boiling Point555.8±60.0 °C(Predicted)
Density1.50±0.1 g/cm3(Predicted)
AppearanceWhite Crystalline Powder
Coloroff-white
Formpowder

Safety & Handling

Warning GHS07 Hazard Statements H315 Causes skin irritation H319 Causes serious eye irritation H335 May cause respiratory irritation Precautionary Statements P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P264 Wash … thoroughly after handling. P271 Use only outdoors or in a well-ventilated area. P280 Wear protective gloves/protective clothing/eye protection/face protection. P319 Get medical advice/attention if you feel unwell. P321 Specific treatment (see … on this label). P405 Store locked up. P501 Dispose of contents/container in accordance with local regulations. P264+P265 Wash … thoroughly after handling. P302+P352 IF ON SKIN: Wash with plenty of water. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P332+P317 Get emergency medical help. P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P403+P233 Store in a well-ventilated place. Keep container tightly closed. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29339900
Storage Class11 - Combustible Solids
WGK (Germany)2

Other Names

A-65006 | Prevacid | Limpidex | Agopton | Lanzor | Takepron | Zoton

Related Products

Chemical Properties

CAS Number
103577-45-3
EC Number
645-308-1
Mol. Weight
369.4
HS Code
29339900

Industries

Documentation