Overview
Omeprazole (CAS 73590-58-6 ), also marketed under the brand names Losec and Prilosec, is a proton pump inhibitor active pharmaceutical ingredient used in the treatment of acid-related gastrointestinal conditions.
As a finished API, it is sourced by pharmaceutical manufacturers and contract formulators for integration into oral solid dosage forms. Omeprazole is the core active in delayed-release capsule and tablet formulations.
These formulations target gastroesophageal reflux disease, peptic ulcers, and Zollinger-Ellison syndrome. Formulators working with enteric-coated pellet systems rely on this API to ensure acid-stable delivery to the small intestine.
It is also incorporated into combination drug products, such as fixed-dose formulations paired with antibiotics for H. pylori eradication regimens. Veterinary pharmaceutical manufacturers source the material for animal treatments.
Omeprazole is supplied as a white to off-white crystalline powder. Standard grades include USP , BP , and Ph. Eur. , with purity specifications typically at 99% or above to meet pharmacopoeial requirements.
Suppliers commonly offer the material in quantities ranging from kilogram-scale for development batches to multi-kilogram lots for commercial manufacturing. This ensures a stable supply chain for global pharmaceutical production.
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Physical Properties
| Melting Point | 156 °C |
| Boiling Point | 600.0±60.0 °C(Predicted) |
| Density | 1.332 g/cm³ |
| Flash Point | 9°C |
| Appearance | White Crystalline Solid |
| Color | white |
| Form | solid |
| Water Solubility | Soluble in water (0.5 mg/ml), DMSO (25 mg/ml), and ethanol (4.5 mg/ml). |
Safety & Handling
Warning GHS07 Hazard Statements H302 Harmful if swallowed Precautionary Statements P264 Wash … thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P330 Rinse mouth. P501 Dispose of contents/container in accordance with local regulations. P301+P317 Get emergency medical help.
Trade & Regulatory
| HS Code | 29333990 |
| UN Number | 1230 |
| Packing Group | II |
| Storage Class | 11 - Combustible Solids |
| WGK (Germany) | 2 |
Other Names
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Chemical Properties
- CAS Number
- 73590-58-6
- EC Number
- 615-996-8
- Mol. Weight
- 345.4
- HS Code
- 29333990
- Category
- Heterocyclic Compounds